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Vyloy Side Effects

Generic name: zolbetuximab

Medically reviewed by Drugs.com. Last updated on Dec 10, 2024.

Note: This document provides detailed information about Vyloy Side Effects associated with zolbetuximab. Some dosage forms listed on this page may not apply specifically to the brand name Vyloy.

Applies to zolbetuximab: intravenous powder for injection.

Important warnings This medicine can cause some serious health issues

Tell your doctor if you use other medicines or have other medical conditions or allergies.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Some side effects may occur during or after the injection with zolbetuximab (the active ingredient contained in Vyloy) including life-threatening allergic reactions and serious infusion-related reactions, which can be fatal.

Call your doctor if you have:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to zolbetuximab: intravenous powder for injection.

General adverse events

The most frequently reported side effects were nausea, vomiting, fatigue, decreased appetite, diarrhea, peripheral sensory neuropathy, abdominal pain, constipation, decreased weight, hypersensitivity reactions, and pyrexia.

The most frequently reported laboratory abnormalities were decreased neutrophil count, decreased leucocyte count, decreased albumin, increased creatinine, decreased hemoglobin, increased glucose, decreased lymphocyte count, increased AST, decreased platelets, increased alkaline phosphatase, increased ALT, decreased glucose, decreased sodium, increased phosphate, decreased potassium, and decreased magnesium.

The most common side effect resulting in discontinuation were nausea and vomiting.[Ref]

Hematologic

Hypersensitivity

Hypersensitivity reactions included anaphylaxis and infusion related reactions.[Ref]

Metabolic

Hepatic

Respiratory

Other

Nervous system

Renal

Cardiovascular

Gastrointestinal

References

1. (2024) "Product Information. Vyloy (zolbetuximab)." Astellas Pharma US, Inc

Further information

Vyloy side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.