Vigamox Side Effects

Generic name: moxifloxacin ophthalmic

Medically reviewed by Drugs.com. Last updated on Feb 3, 2025.

Note: This document provides detailed information about Vigamox Side Effects associated with moxifloxacin ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Vigamox.

Applies to moxifloxacin ophthalmic: ophthalmic solution.

Precautions

If your or your child's eye infection does not improve within a few days, or if it becomes worse, check with your doctor.

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Check with your doctor right away if you have blurred or decreased vision, pooling of whitish fluid visible on the colored part of the eye, seeing floating spots before the eyes, or swelling of the eye. These may be symptoms of an eye problem called toxic anterior segment syndrome (TASS).

Do not wear contact lenses while you are using this medicine to avoid further eye irritation.

Common side effects of Vigamox

Some side effects of moxifloxacin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Vigamox

Along with its needed effects, moxifloxacin ophthalmic (the active ingredient contained in Vigamox) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking moxifloxacin ophthalmic:

For healthcare professionals

Applies to moxifloxacin ophthalmic: intraocular solution, ophthalmic solution.

General adverse events

The most common side effects were eye irritation and eye pain.

Ocular

• Common (1% to 10%): Conjunctivitis, decreased visual acuity, dry eye, keratitis, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, subconjunctival hemorrhage, tearing, eye irritation, eye pain
• Uncommon (0.1% to 1%): Punctuate keratitis, eye pruritus, conjunctival hemorrhage, eyelid edema
• Rare (less than 0.1%): Corneal epithelium defect, corneal disorder, blepharitis, eye swelling, conjunctival edema, blurred vision, asthenopia, erythema of eyelid
• Frequency not reported: Endophthalmitis, ulcerative keratitis, corneal erosion, corneal abrasion, intraocular pressure increased, corneal opacity, corneal infiltrates, corneal deposits, eye allergy, corneal edema, photophobia, lacrimation increased, eye discharge, foreign body sensation in eyes, corneal staining, eyelid disorder, abnormal sensation in eye^[Ref]

Respiratory

• Common (1% to 10%): Increased cough, pharyngitis, rhinitis
• Rare (less than 0.1%): Nasal discomfort, pharyngolaryngeal pain, sensation of foreign body (throat)
• Frequency not reported: Dyspnea^[Ref]

Dermatologic

• Common (1% to 10%): Rash
• Frequency not reported: Erythema, pruritus, urticaria^[Ref]

Other

• Common (1% to 10%): Otitis media, fever/pyrexia, infection^[Ref]

Nervous system

• Uncommon (0.1% to 1%): Dysgeusia, headache
• Rare (less than 0.1%): Paresthesia
• Frequency not reported: Dizziness^[Ref]

Gastrointestinal

• Rare (less than 0.1%): Vomiting
• Frequency not reported: Nausea^[Ref]

Hematologic

• Rare (less than 0.1%): Decreased hemoglobin^[Ref]

Hepatic

• Rare (less than 0.1%): Increased ALT, increased GGT^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity

Systemic quinolones:

• Frequency not reported: Hypersensitivity (anaphylactic) reactions^[Ref]

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions (some after first dose) have been reported with systemic quinolones.^[Ref]

Cardiovascular

• Frequency not reported: Palpitations^[Ref]

Musculoskeletal

Systemic fluoroquinolones:

• Frequency not reported: Tendon ruptures^[Ref]

Ruptures of the shoulder, hand, Achilles, or other tendons (requiring surgical repair or resulting in prolonged disability) have been reported with systemic fluoroquinolones. Risk of such ruptures may be increased in patients using concomitant corticosteroids, especially geriatric patients and in tendons under high stress (including the Achilles tendon).^[Ref]

See also:

Further information

Vigamox side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer