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Vigamox Side Effects

Generic Name: moxifloxacin ophthalmic

Note: This document contains side effect information about moxifloxacin ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Vigamox.

For the Consumer

Applies to moxifloxacin ophthalmic: ophthalmic solution

Along with its needed effects, moxifloxacin ophthalmic (the active ingredient contained in Vigamox) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking moxifloxacin ophthalmic:

Incidence not known
  • Fainting or loss of consciousness
  • fast or irregular breathing
  • itching or skin rash
  • swelling of the eyes or eyelids
  • tightness in the chest
  • trouble with breathing

Some side effects of moxifloxacin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning, dry, or itching eyes
  • change in vision
  • decreased vision
  • dry eye
  • excessive tearing
  • eye discharge
  • itching of the eye
  • pain in the eye
  • red, sore eyes
  • tearing
Less common
  • Body aches or pain
  • congestion
  • cough or hoarseness
  • decreased hearing
  • dryness or soreness of the throat
  • fever or chills
  • general body discomfort
  • lower back or side pain
  • painful or difficult urination
  • rubbing or pulling of the ears (in children)
  • runny nose
  • sore throat
  • tender, swollen glands in the neck
  • trouble with swallowing
  • voice changes
  • vomiting and diarrhea (in infants)

For Healthcare Professionals

Applies to moxifloxacin ophthalmic: ophthalmic solution

General

The most common side effects were eye irritation and eye pain.

Ocular

Common (1% to 10%): Conjunctivitis, decreased visual acuity, dry eye, keratitis, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, subconjunctival hemorrhage, tearing, eye irritation, eye pain
Uncommon (0.1% to 1%): Punctuate keratitis, eye pruritus, conjunctival hemorrhage, eyelid edema
Rare (less than 0.1%): Corneal epithelium defect, corneal disorder, blepharitis, eye swelling, conjunctival edema, blurred vision, asthenopia, erythema of eyelid
Frequency not reported: Endophthalmitis, ulcerative keratitis, corneal erosion, corneal abrasion, intraocular pressure increased, corneal opacity, corneal infiltrates, corneal deposits, eye allergy, corneal edema, photophobia, lacrimation increased, eye discharge, foreign body sensation in eyes, corneal staining, eyelid disorder, abnormal sensation in eye[Ref]

Respiratory

Common (1% to 10%): Increased cough, pharyngitis, rhinitis
Rare (less than 0.1%): Nasal discomfort, pharyngolaryngeal pain, sensation of foreign body (throat)
Frequency not reported: Dyspnea[Ref]

Dermatologic

Common (1% to 10%): Rash
Frequency not reported: Erythema, pruritus, urticaria[Ref]

Other

Common (1% to 10%): Otitis media, fever/pyrexia, infection[Ref]

Nervous system

Uncommon (0.1% to 1%): Dysgeusia, headache
Rare (less than 0.1%): Paresthesia
Frequency not reported: Dizziness[Ref]

Gastrointestinal

Rare (less than 0.1%): Vomiting
Frequency not reported: Nausea[Ref]

Hematologic

Rare (less than 0.1%): Decreased hemoglobin[Ref]

Hepatic

Rare (less than 0.1%): Increased ALT, increased GGT[Ref]

Hypersensitivity

Serious and occasionally fatal hypersensitivity (anaphylactic) reactions (some after first dose) have been reported with systemic quinolones.[Ref]

Frequency not reported: Hypersensitivity

Systemic quinolones:
-Frequency not reported: Hypersensitivity (anaphylactic) reactions[Ref]

Cardiovascular

Frequency not reported: Palpitations[Ref]

Musculoskeletal

Systemic fluoroquinolones:
-Frequency not reported: Tendon ruptures[Ref]

Ruptures of the shoulder, hand, Achilles, or other tendons (requiring surgical repair or resulting in prolonged disability) have been reported with systemic fluoroquinolones. Risk of such ruptures may be increased in patients using concomitant corticosteroids, especially geriatric patients and in tendons under high stress (including the Achilles tendon).[Ref]

References

1. "Product Information. Moxeza (moxifloxacin ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

2. "Product Information. Vigamox (moxifloxacin ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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