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Tusscough DHC Side Effects

Generic Name: chlorpheniramine / dihydrocodeine / phenylephrine

Note: This document contains side effect information about chlorpheniramine / dihydrocodeine / phenylephrine. Some of the dosage forms listed on this page may not apply to the brand name Tusscough DHC.

For the Consumer

Applies to chlorpheniramine / dihydrocodeine / phenylephrine: oral liquid

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop using this medicine and call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;

  • a light-headed feeling, like you might pass out;

  • severe anxiety, confusion, fear;

  • painful or difficult urination;

  • little or no urinating; or

  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects may include:

  • dizziness, drowsiness, headache;

  • nausea, upset stomach;

  • constipation;

  • blurred vision; or

  • dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to chlorpheniramine / dihydrocodeine / phenylephrine: oral liquid, oral syrup

General

General side effects including light-headedness, dizziness, drowsiness, headache, fatigue, and sedation have been among the most frequently reported with opioid use. Confusion, abdominal pain, lassitude, giddiness, increased irritability or excitement (especially in children) have been reported. Hallucinations, severe narcosis, and vivid dreams have been reported rarely.[Ref]

Gastrointestinal

Gastrointestinal side effects including nausea, vomiting, and constipation have been among the most frequently reported with opioid use. Diarrhea, dry mouth, indigestion, anorexia, spasm of biliary tract have been reported.[Ref]

Dermatologic

Dermatologic side effects including sweating, pruritus, and skin reactions have been among the most frequently reported with opioid use. Flushing has been reported.[Ref]

Other

Symptoms of dihydrocodeine withdrawal consist of irritability, restlessness, insomnia, diaphoresis, anxiety, and palpitations.[Ref]

Other side effects of dihydrocodeine have included psychological dependence, physical dependence, and tolerance have been reported to develop upon repeated administration.[Ref]

Renal

Renal side effects including granulomatous interstitial nephritis and acute renal failure have been reported rarely during dihydrocodeine administration.[Ref]

Cardiovascular

Cardiovascular side effects including orthostatic hypotension and cardiac palpitations have been reported.[Ref]

Respiratory

Respiratory side effects including respiratory depression have been reported.[Ref]

Ocular

Ocular side effects including miosis and blurred vision have been reported.[Ref]

Genitourinary

Genitourinary side effects including urinary retention have been reported.[Ref]

Hypersensitivity

Hypersensitivity side effects including anaphylactoid reactions have been reported rarely.[Ref]

References

1. "Product Information. Pancof-PD (chlorpheniramine / dihydrocodeine / phenylephrine)." Pamlab LLC, Mandeville, LA.

Some side effects of Tusscough DHC may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Tusscough DHC (chlorpheniramine / dihydrocodeine / phenylephrine)

Consumer resources

Other brands: DiHydro-PE, Novahistine DH

Professional resources

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Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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