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Brompheniramine, dextromethorphan, and pseudoephedrine

Generic name: brompheniramine, dextromethorphan, and pseudoephedrine [ brom-fen-EER-a-meen, dex-troe-me-THOR-fan, soo-doe-e-FED-rin ]
Brand names: BroveX PSE DM, Allanhist PDX Drops, Anaplex DM, Andehist DM NR Syrup, Bromaline DM, ... show all 41 brands
Dosage forms: oral syrup (2 mg-10 mg-30 mg/5 mL), oral tablet (4 mg-20 mg-40 mg)
Drug class: Upper respiratory combinations

Medically reviewed by Drugs.com on Oct 23, 2023. Written by Cerner Multum.

What is brompheniramine, dextromethorphan, and pseudoephedrine?

Brompheniramine is an antihistamine. Dextromethorphan is a cough suppressant. Pseudoephedrine is a decongestant.

Brompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, and watery eyes caused by allergies or the common cold.

Brompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide.

brompheniramine, dextromethorphan, and pseudoephedrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

Common side effects of brompheniramine, dextromethorphan, and pseudoephedrine may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use this medicine if you are allergic to it brompheniramine, dextromethorphan, or pseudoephedrine, or if you have:

Do not use brompheniramine, dextromethorphan, and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant.

Do not breastfeed.

How should I take brompheniramine, dextromethorphan, and pseudoephedrine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Follow all directions when giving this medicine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need surgery or medical tests, tell the doctor ahead of time if you have taken this medicine within the past few days.

Store tightly closed at room temperature, away from moisture and heat.

Bromfed DM, brompheniramine / dextromethorphan / pseudoephedrine, Mucinex D, Promethazine VC with Codeine

What happens if I miss a dose?

brompheniramine, dextromethorphan, and pseudoephedrine is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

Do not take more than 6 doses in 24 hours.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling depressed or restless, fast or irregular heartbeats, severe drowsiness, loss of coordination, or seizure.

What should I avoid while taking brompheniramine, dextromethorphan, and pseudoephedrine?

Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating and you may be more prone to heat stroke.

Drinking alcohol with this medicine can cause side effects.

What other drugs will affect brompheniramine, dextromethorphan, and pseudoephedrine?

Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Does brompheniramine/dextromethorphan/pseudoephedrine interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.