Targiniq ER Side Effects
Generic Name: naloxone / oxycodone
Note: This document contains side effect information about naloxone / oxycodone. Some of the dosage forms listed on this page may not apply to the brand name Targiniq ER.
Common (1% to 10%): Hypertension, hypotension
Rare (less than 0.1%): Syncope
Common (1% to 10%): Pruritus, rash, cold sweat
Common (1% to 10%): Hot flush[Ref]
Frequency not reported: Biliary colic, increased liver enzymes, biliary spasm, cholestasis[Ref]
Common (1% to 10%): Influenza
Rare (less than 0.1%): Herpes simplex
Common (1% to 10%): Loss of appetite
Rare (less than 0.1%): Dehydration, increased appetite
Common (1% to 10%): Back pain, fall, arthralgia, myalgia
Frequency not reported: Myalgia, neck pain, striated and nonstriated muscle spasms, muscle twitching, muscle rigidity, osteoarthritis, abnormal gait, hypertonia, involuntary muscle contractions, abnormal coordination[Ref]
Uncommon (0.1% to 1%): Disturbance in attention, paraesthesia, speech disorder, malaise
Rare (less than 0.1%): Convulsions (particularly in persons with epileptic disorder or predisposition to convulsions)
Frequency not reported: Syncope
Postmarketing reports: Raised intracranial pressure, sciatica, tremor, vertigo, drowsiness, paraesthesia, somnolence, speech disorder, amnesia, hypertonia, migraine, feeling hot and cold, chills, tinnitus[Ref]
Common (1% to 10%): Lacrimation increased
Uncommon (0.1% to 1%): Visual disturbances, miosis[Ref]
Common (1% to 10%): Malignant neoplasm progression
Uncommon (0.1% to 1%): Abnormal thinking, confusion, depression, hallucination, altered mood, personality change, euphoric mood, decreased activity, psychomotor hyperactivity, agitation, nervousness, insomnia, perception disturbances (e.g., hallucination, derealization), reduced libido, mood changes, disorientation, dysphoria, nightmares[Ref]
Common (1% to 10%): Dyspnea, rhinorrhea, yawning
Uncommon (0.1% to 1%): Respiratory depression, bronchial spasm, spasms of nonstriated muscles, suppression of the cough reflex
1. "Product Information. Targiniq ER (naloxone-oxyCODONE)." Purdue Pharma LP, Stamford, CT.
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Cerner Multum, Inc. "Australian Product Information." O 0
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.