SennaPrompt Side Effects
Generic name: psyllium/senna
Note: This document provides detailed information about SennaPrompt.
Applies to psyllium/senna: oral capsule, oral granule for reconstitution.
Gastrointestinal adverse events
Gastrointestinal side effects have included several cases of esophageal impaction and duodenal bezoars in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (commercially available as Perdiem Overnight Relief).[Ref]
Hypersensitivity
Hypersensitivity side effects have been reported rarely. They have included sensitization to psyllium resulting from inhalation of fine dust particles dispersed into the air as the product is mixed or poured. Occupational sensitization to senna has been reported rarely.[Ref]
While hypersensitivity reactions to psyllium may be severe, they are most frequently reported by workers in the pharmaceutical firms that manufacture the drug. This is because when it is mixed or poured, fine dust particles are readily dispersed into the air and can then be inhaled and cause sensitization. Orally ingested psyllium seems less likely to induce sensitization Side Effects associated with psyllium/senna. Some dosage forms listed on this page may not apply specifically to the brand name SennaPrompt.
Applies to psyllium/senna: oral capsule, oral granule for reconstitution.
Gastrointestinal adverse events
Gastrointestinal side effects have included several cases of esophageal impaction and duodenal bezoars in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (commercially available as Perdiem Overnight Relief).[Ref]
Hypersensitivity
Hypersensitivity side effects have been reported rarely. They have included sensitization to psyllium resulting from inhalation of fine dust particles dispersed into the air as the product is mixed or poured. Occupational sensitization to senna has been reported rarely.[Ref]
While hypersensitivity reactions to psyllium may be severe, they are most frequently reported by workers in the pharmaceutical firms that manufacture the drug. This is because when it is mixed or poured, fine dust particles are readily dispersed into the air and can then be inhaled and cause sensitization. Orally ingested psyllium seems less likely to induce sensitization.
A case has been reported of a factory worker who developed IgE-mediated asthma and rhinoconjunctivitis five months after exposure to senna.[Ref]
Hematologic
Hematologic side effects have included a case of eosinophilia in a patient receiving psyllium.[Ref]
The case report of eosinophilia was believed to be a sole manifestation of an allergic reaction to psyllium.[Ref]
Musculoskeletal
Musculoskeletal side effects include a case of finger clubbing presumed to be associated with senna use.[Ref]
References
1. Angueira C, Kadakia S (1993) "Esophageal and duodenal bezoars from Perdiem [letter]." Gastrointest Endosc, 39, p. 110-1
2. Schneider RP (1989) "Perdiem causes esophageal impaction and bezoars." South Med J, 82, p. 1449-50
3. "Product Information. Perdiem (psyllium-senna)." Novartis Pharmaceuticals
4. Gillespie BF, Rathbun FJ (1992) "Adverse effects of psyllium." CMAJ, 146, p. 16-7
5. Helin T, Makinen-Kiljunen S (1996) "Occupational asthma and rhinoconjunctivitis caused by senna." Allergy, 51, p. 181-4
6. Nelson AM, Taubin HL, Frank HD (1980) "Eosinophilia associated with psyllium hydrophilic colloid ingestion [letter." JAMA, 243, p. 329-30
7. Prior J, White I (1978) "Tetany and clubbing in patient who ingested large quantities of senna [letter." Lancet, 2, p. 947
8. Malmquist J, Ericsson B, Hulten-Nosslin MB, Jeppsson JO, Ljungberg O (1980) "Finger clubbing and aspartylglucosamine excretion in a laxative- abusing patient." Postgrad Med J, 56, p. 862-4
More about SennaPrompt (psyllium/senna)
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- During pregnancy
- Drug class: laxatives
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Further information
SennaPrompt side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
