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Razadyne ER Side Effects

Generic Name: galantamine

Note: This document contains side effect information about galantamine. Some of the dosage forms listed on this page may not apply to the brand name Razadyne ER.

In Summary

Common side effects of Razadyne ER include: nausea and vomiting. Other side effects include: dizziness, dyspepsia, fatigue, headache, weight loss, diarrhea, and anorexia. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to galantamine: oral capsule extended release, oral solution, oral tablet

Along with its needed effects, galantamine (the active ingredient contained in Razadyne ER) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking galantamine:

Less common

  • Chest pain or discomfort
  • lightheadedness, dizziness, or fainting
  • shakiness in the legs, arms, hands, or feet
  • shortness of breath
  • slow or irregular heartbeat
  • unusual tiredness


  • Blurred vision
  • confusion
  • decreased urination
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • fainting
  • fast, irregular, pounding, or racing heartbeat or pulse
  • feeling of warmth
  • rapid breathing
  • redness of the face, neck, arms, and occasionally, upper chest
  • sunken eyes
  • sweating
  • thirst
  • troubled breathing
  • unusual tiredness or weakness
  • wrinkled skin

Incidence not known

  • Blistering, peeling, or loosening of the skin
  • chills
  • cough
  • dark urine
  • fever
  • general tiredness and weakness
  • headache
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • light-colored stools
  • nausea and vomiting
  • nervousness
  • pounding in the ears
  • rash, hives, or itching skin
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • redness of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled swallowing
  • upper right abdominal or stomach pain
  • yellow eyes and skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking galantamine:

Symptoms of overdose

  • Confusion
  • convulsions
  • irregular, fast or slow, or shallow breathing
  • muscle weakness
  • pale or blue lips, fingernails, or skin
  • severe nausea
  • stomach cramps
  • sweating
  • tearing of the eyes
  • twitches of the muscle visible under the skin
  • vomiting

Some side effects of galantamine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

  • Acid or sour stomach
  • belching
  • discouragement
  • feeling sad or empty
  • general feeling of discomfort or illness
  • heartburn
  • increased sweating
  • indigestion
  • irritability
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • muscle spasms
  • stomach discomfort, upset, or pain
  • trouble concentrating
  • trouble sleeping
  • unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness


  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • dry heaves
  • loss of taste
  • unusually deep sleep
  • unusually long duration of sleep

Incidence not known

  • Continuing ringing or buzzing or other unexplained noise in the ears
  • hearing loss
  • seeing, hearing, or feeling things that are not there

For Healthcare Professionals

Applies to galantamine: oral capsule extended release, oral solution, oral tablet


Common (1% to 10%): Bradycardia
Uncommon (0.1% to 1%): First degree atrioventricular block, palpitations, sinus bradycardia, supraventricular extrasystoles, flushing, hypotension
Frequency not reported: Postural hypotension, dependent edema, cardiac failure, myocardial ischemia or infarction, atrial arrhythmias including atrial fibrillation and supraventricular tachycardia, QT prolonged, bundle branch block, T-wave inversion, chest pain and ventricular tachycardia
Postmarketing reports: Hypertension[Ref]


Common (1% to 10%): Hyperhidrosis


Very common (10% or more): Nausea, vomiting
Common (1% to 10%): Diarrhea, abdominal pain, upper abdominal pain, dyspepsia, stomach discomfort, abdominal discomfort
Uncommon (0.1% to 1%): Retching
Postmarketing reports: Upper and lower GI bleeding, stomach discomfort, and abdominal discomfort.[Ref]


The most common side effects associated with discontinuation were nausea, vomiting, decreased appetite, dizziness, diarrhea, headache, decreased weight, and abdominal pain.[Ref]


Common (1% to 10%): Urinary tract infection, hematuria
Frequency not reported: Increased libido[Ref]


Common (1% to 10%): Anemia[Ref]


Postmarketing reports: Hepatitis, increased hepatic enzymes


Postmarketing reports: Hypersensitivity


Common (1% to 10%): Decreased appetite, decreased weight, anorexia
Uncommon (0.1% to 1%): Dehydration


Common (1% to 10%): Muscle spasms
Uncommon (0.1% to 1%): Muscular weakness

Nervous system

Common (1% to 10%): Dizziness, headache, tremor, syncope, lethargy, somnolence
Uncommon (0.1% to 1%): Dysgeusia, hypersomnia, paresthesia
Frequency not reported: Insomnia, leg cramps, transient ischemic attacks, cerebrovascular accidents
Postmarketing reports: Tinnitus[Ref]


Uncommon (0.1% to 1%): Blurred vision


Common (1% to 10%): Fatigue, asthenia, malaise
Uncommon (0.1% to 1%): Fall
Frequency not reported: Death in patients with mild cognitive impairment, fever


Common (1% to 10%): Depression
Frequency not reported: Apathy, paranoia (disagreeable or terrifying dreams), paranoid reaction, increased libido, delirium, suicidal ideation and suicide
Postmarketing reports: Hallucination, visual hallucination, auditory hallucination[Ref]


Common (1% to 10%): Rhinitis[Ref]


1. "Product Information. Reminyl (galantamine)" Janssen Pharmaceuticals, Titusville, NJ.

2. "Product Information. Razadyne (galantamine)." Ortho McNeil Pharmaceutical, Raritan, NJ.

3. Iraqi A, Hughes TL "An unusual case of nightmares with galantamine." J Am Geriatr Soc 57 (2009): 565

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.