Phenylephrine / Triprolidine Side Effects
Medically reviewed by Drugs.com. Last updated on Dec 1, 2023.
Applies to phenylephrine / triprolidine: oral liquid.
Important warnings
This medicine can cause some serious health issues
You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate.
Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid.
Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
Get emergency medical help if you have any of these signs of an allergic reaction while taking phenylephrine / triprolidine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect such as:
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fast or uneven heart rate;
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mood changes;
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tremor, seizure (convulsions);
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easy bruising or bleeding, unusual weakness;
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urinating less than usual or not at all;
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feeling short of breath; or
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dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).
Less serious side effects of phenylephrine / triprolidine may include:
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dizziness, drowsiness;
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dry mouth, nose, or throat;
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constipation;
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blurred vision; or
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feeling nervous or restless.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
See also:
More about phenylephrine / triprolidine
- Check interactions
- Compare alternatives
- Dosage information
- Drug class: upper respiratory combinations
Patient resources
Other brands
Related treatment guides
Further information
Phenylephrine/triprolidine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.