Paser Side Effects

Generic name: aminosalicylic acid

Medically reviewed by Drugs.com. Last updated on Sep 22, 2024.

Note: This document provides detailed information about Paser.

Applies to aminosalicylic acid: oral delayed-release granules Side Effects associated with aminosalicylic acid. Some dosage forms listed on this page may not apply specifically to the brand name Paser.

Applies to aminosalicylic acid: oral delayed-release granules.

Side effects include:

GI effects (nausea, vomiting, abdominal pain, diarrhea).

For healthcare professionals

Applies to aminosalicylic acid: compounding powder, oral granule enteric coated.

Gastrointestinal adverse events

• Common (1% to 10%): Abdominal pain, bloating, diarrhea, gastrointestinal intolerance, nausea, soft stools, vomiting
• Rare (0.01% to 0.1%): Gastrointestinal bleeding, malabsorption syndrome, peptic ulcer^[Ref]

Gastrointestinal intolerance was manifested by abdominal pain, diarrhea, nausea, and vomiting.^[Ref]

Nervous system

• Common (1% to 10%): Giddiness, vestibular syndrome
• Rare (0.01% to 0.1%): Metallic taste
• Very rare (less than 0.01%): Dizziness, headache, peripheral neuropathy
• Frequency not reported: Encephalopathy, optic neuritis^[Ref]

Dermatologic

• Common (1% to 10%): Cutaneous hypersensitivity, skin rash
• Rare (0.01% to 0.1%): Urticaria
• Very rare (less than 0.01%): Purpura
• Frequency not reported: Exfoliative dermatitis, skin eruptions of various types^[Ref]

Endocrine

• Common (1% to 10%): Hypothyroidism^[Ref]

Hypothyroidism most commonly occurred in patients with HIV, especially when this drug was given with ethionamide or prothionamide. When patients without HIV were given this drug, hypothyroidism rarely occurred.^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Anorexia
• Very rare (less than 0.01%): Hypoglycemia, weight loss^[Ref]

Hepatic

• Rare (0.01% to 0.1%): Jaundice
• Very rare (less than 0.01%): Hepatocytolysis, increased blood alkaline phosphatase, increased transaminases
• Frequency not reported: Hepatitis^[Ref]

Patients should be closely monitored during the first three months of therapy and treatment must be discontinued immediately at the first signs of rash, fever, jaundice, or other sign of intolerance.^[Ref]

Hematologic

• Very rare (less than 0.01%): Agranulocytosis, anemia, decreased prothrombin level, leukopenia, methemoglobinemia, thrombocytopenia
• Frequency not reported: Coombs' positive hemolytic anemia, lymphoma-like syndrome^[Ref]

Genitourinary

• Very rare (less than 0.01%): Crystalluria^[Ref]

Ocular

• Very rare (less than 0.01%): Visual abnormalities^[Ref]

Musculoskeletal

• Very rare (less than 0.01%): Tendon pain^[Ref]

Cardiovascular

• Frequency not reported: Pericarditis, vasculitis^[Ref]

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions^[Ref]

Immunologic

• Frequency not reported: Infectious mononucleosis-like skin eruptions^[Ref]

Respiratory

• Frequency not reported: Loeffler's syndrome^[Ref]

Other

• Frequency not reported: Fever^[Ref]

Further information

Paser side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer