Skip to main content

Paser Side Effects

Generic name: aminosalicylic acid

Medically reviewed by Last updated on Mar 8, 2023.

Note: This document contains side effect information about aminosalicylic acid. Some dosage forms listed on this page may not apply to the brand name Paser.

Applies to aminosalicylic acid: oral delayed-release granules.

Side effects include:

GI effects (nausea, vomiting, abdominal pain, diarrhea).

For Healthcare Professionals

Applies to aminosalicylic acid: compounding powder, oral granule enteric coated.


Gastrointestinal intolerance was manifested by abdominal pain, diarrhea, nausea, and vomiting.[Ref]

Common (1% to 10%): Abdominal pain, bloating, diarrhea, gastrointestinal intolerance, nausea, soft stools, vomiting

Rare (0.01% to 0.1%): Gastrointestinal bleeding, malabsorption syndrome, peptic ulcer[Ref]

Nervous system

Common (1% to 10%): Giddiness, vestibular syndrome

Rare (0.01% to 0.1%): Metallic taste

Very rare (less than 0.01%): Dizziness, headache, peripheral neuropathy

Frequency not reported: Encephalopathy, optic neuritis[Ref]


Common (1% to 10%): Cutaneous hypersensitivity, skin rash

Rare (0.01% to 0.1%): Urticaria

Very rare (less than 0.01%): Purpura

Frequency not reported: Exfoliative dermatitis, skin eruptions of various types[Ref]


Hypothyroidism most commonly occurred in patients with HIV, especially when this drug was given with ethionamide or prothionamide. When patients without HIV were given this drug, hypothyroidism rarely occurred.[Ref]

Common (1% to 10%): Hypothyroidism[Ref]


Uncommon (0.1% to 1%): Anorexia

Very rare (less than 0.01%): Hypoglycemia, weight loss[Ref]


Patients should be closely monitored during the first three months of therapy and treatment must be discontinued immediately at the first signs of rash, fever, jaundice, or other sign of intolerance.[Ref]

Rare (0.01% to 0.1%): Jaundice

Very rare (less than 0.01%): Hepatocytolysis, increased blood alkaline phosphatase, increased transaminases

Frequency not reported: Hepatitis[Ref]


Very rare (less than 0.01%): Agranulocytosis, anemia, decreased prothrombin level, leukopenia, methemoglobinemia, thrombocytopenia

Frequency not reported: Coombs' positive hemolytic anemia, lymphoma-like syndrome[Ref]


Very rare (less than 0.01%): Crystalluria[Ref]


Very rare (less than 0.01%): Visual abnormalities[Ref]


Very rare (less than 0.01%): Tendon pain[Ref]


Frequency not reported: Pericarditis, vasculitis[Ref]


Frequency not reported: Hypersensitivity reactions[Ref]


Frequency not reported: Infectious mononucleosis-like skin eruptions[Ref]


Frequency not reported: Loeffler's syndrome[Ref]


Frequency not reported: Fever[Ref]


1. Product Information. Paser D/R (aminosalicylic acid). Jacobus Pharmaceutical Company.

2. Cerner Multum, Inc. UK Summary of Product Characteristics.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.