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Minocycline topical Side Effects

For the Consumer

Applies to minocycline topical: subgingival powder

In addition to its needed effects, some unwanted effects may be caused by minocycline topical. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking minocycline topical:

More common:
  • Bleeding from the gums
  • chills
  • dental pain
  • fever
  • pain, redness, and swelling in the mouth
  • problems with teeth
  • redness or swelling of the gums
  • toothache
Less common:
  • Bad taste in the mouth
  • discharge from the gums
  • foul breath odor
  • painful sores in the mouth
  • problems in the lining of the mouth

Minor Side Effects

Some of the side effects that can occur with minocycline topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Headache
Less common:
  • Acid or sour stomach
  • belching
  • cough
  • heartburn
  • increased sensitivity to sunlight
  • indigestion
  • pain
  • pain in the joints or muscles
  • runny nose
  • sneezing
  • sore throat
  • stomach discomfort, upset, or pain

For Healthcare Professionals

Applies to minocycline topical: mucous membrane insert

General

Minocycline topical powder is intended for local application only. Systemic effects from the absorption of small amounts of the drug are unlikely.[Ref]

Other

Other side effects have included headache (9%) and pain (4.3%).[Ref]

Dermatologic

Dermatologic side effects have included stomatitis (6.4%), mouth ulceration (5%), and mucous membrane disorder (3.3%).[Ref]

Gastrointestinal

Gastrointestinal side effects have included dyspepsia (4%).[Ref]

Local

Local side effects have included periodontitis (16.3%), tooth disorder (12.3%), tooth caries (9.9%), dental pain (9.9%), gingivitis (9.2%), pharyngitis (4.3%), and dental infection (3.8%).[Ref]

Immunologic

Immunologic side effects have included flu syndrome (5%) and infection (7.6%).[Ref]

References

1. "Product Information. Arestin (minocycline topical)" OraPharma, Inc, Warminster, PA.

Not all side effects for minocycline topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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