Minocycline Topical Side Effects

Medically reviewed by Drugs.com. Last updated on May 9, 2024.

Applies to minocycline topical: subgingival powder.

Other dosage forms:

• topical application foam

Precautions

Check with your dentist as soon as possible if you have pain or swelling or other problems in the treated areas.

It is very important that your dentist check your progress. Do not miss any dental appointments.

Tetracyclines, such as minocycline, may cause your skin to be more sensitive to sunlight than normal. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. After receiving minocycline:

• Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
• Wear protective clothing, including a hat. Also, wear sunglasses.
• Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.
• Apply a sun block lip balm or lipstick that has an SPF of at least 15 to protect your lips.
• Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your dentist or doctor.

Serious side effects of minocycline topical

Along with its needed effects, minocycline topical may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking minocycline topical:

Other side effects of minocycline topical

Some side effects of minocycline topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to minocycline topical: mucous membrane insert, topical foam.

General adverse events

Minocycline topical powder is intended for local application only. Systemic effects from the absorption of small amounts of the drug are unlikely.^[Ref]

Other

Other side effects have included headache (9%) and pain (4.3%).^[Ref]

Dermatologic

Dermatologic side effects have included stomatitis (6.4%), mouth ulceration (5%), and mucous membrane disorder (3.3%).^[Ref]

Gastrointestinal

Gastrointestinal side effects have included dyspepsia (4%).^[Ref]

Local

Local side effects have included periodontitis (16.3%), tooth disorder (12.3%), tooth caries (9.9%), dental pain (9.9%), gingivitis (9.2%), pharyngitis (4.3%), and dental infection (3.8%).^[Ref]

Immunologic

Immunologic side effects have included flu syndrome (5%) and infection (7.6%).^[Ref]

See also:

Further information

Minocycline topical side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer