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Levocabastine ophthalmic Side Effects

Medically reviewed by Last updated on Oct 17, 2022.

Applies to levocabastine ophthalmic: ophthalmic suspension.


In general, levocabastine is very well tolerated with minimal adverse effects. Most studies have indicated that the percent of adverse reactions with levocabastine occur with similar frequency on placebo. Local mild, transient stinging and burning appear to be the most common adverse effect occurring in approximately 25% of patients. Adverse effects do not appear to be dose-related.[Ref]

Nervous system

Nervous system adverse effects have included headache (5%), dry mouth, fatigue, and somnolence.[Ref]


Ocular side effects have included stinging, burning, visual disturbances, eye pain, eye dryness, red eyes, eyelid edema, lacrimation, and eye discharge.[Ref]


Gastrointestinal side effects have included nausea.[Ref]


Respiratory side effects have included dyspnea, pharyngitis, and cough.[Ref]


Dermatologic side effects have included rash and erythema.[Ref]


1. Dechant KL, Goa KL "Levocabastine. A review of its pharmacological properties and therapeutic potential as a topical antihistamine in allergic rhinitis and conjunctivitis." Drugs 41 (1991): 202-24

2. "Product Information. Livostin (levocabastine ophthalmic)." Ciba Vision Ophthalmics

3. Rombaut N, Bhatti JZ, Curran S, Hindmarch I "Effects of topical administration of levocabastine on psychomotor and cognitive function." Ann Allergy 67 (1991): 75-9

4. Knight A "The role of levocabastine in the treatment of allergic rhinoconjunctivitis." Br J Clin Pract 48 (1994): 139-43

5. Bahmer FA "Topical levocabastine - an effective alternative to oral antihistamines in seasonal allergic rhinoconjunctivitis." Clin Exp Allergy 25 (1995): 220-7

Further information

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Some side effects may not be reported. You may report them to the FDA.