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Levocabastine ophthalmic Side Effects

Applies to levocabastine ophthalmic: ophthalmic suspension


In general, levocabastine is very well tolerated with minimal adverse effects. Most studies have indicated that the percent of adverse reactions with levocabastine occur with similar frequency on placebo. Local mild, transient stinging and burning appear to be the most common adverse effect occurring in approximately 25% of patients. Adverse effects do not appear to be dose-related.[Ref]

Nervous system

Nervous system adverse effects have included headache (5%), dry mouth, fatigue, and somnolence.[Ref]


Ocular side effects have included stinging, burning, visual disturbances, eye pain, eye dryness, red eyes, eyelid edema, lacrimation, and eye discharge.[Ref]


Gastrointestinal side effects have included nausea.[Ref]


Respiratory side effects have included dyspnea, pharyngitis, and cough.[Ref]


Dermatologic side effects have included rash and erythema.[Ref]


1. Dechant KL, Goa KL "Levocabastine. A review of its pharmacological properties and therapeutic potential as a topical antihistamine in allergic rhinitis and conjunctivitis." Drugs 41 (1991): 202-24

2. "Product Information. Livostin (levocabastine)." Ciba Vision Ophthalmics, Duluth, GA.

3. Rombaut N, Bhatti JZ, Curran S, Hindmarch I "Effects of topical administration of levocabastine on psychomotor and cognitive function." Ann Allergy 67 (1991): 75-9

4. Knight A "The role of levocabastine in the treatment of allergic rhinoconjunctivitis." Br J Clin Pract 48 (1994): 139-43

5. Bahmer FA "Topical levocabastine - an effective alternative to oral antihistamines in seasonal allergic rhinoconjunctivitis." Clin Exp Allergy 25 (1995): 220-7

Not all side effects for levocabastine ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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