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Lastacaft Side Effects

Generic Name: alcaftadine ophthalmic

Note: This document contains side effect information about alcaftadine ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Lastacaft.

For the Consumer

Applies to alcaftadine ophthalmic: ophthalmic solution

Along with its needed effects, alcaftadine ophthalmic (the active ingredient contained in Lastacaft) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking alcaftadine ophthalmic:

Less common
  • Burning or stinging sensation in the eye
  • itching of the eyes
  • red, sore eyes

Some side effects of alcaftadine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to alcaftadine ophthalmic: ophthalmic solution


The most commonly reported side effects were eye irritation, burning and/or stinging upon instillation, eye redness, and eye pruritus.[Ref]


Postmarketing reports: Hypersensitivity reactions (including swelling of the face or allergic dermatitis)[Ref]


Frequency not reported: Eye irritation, burning and/or stinging upon instillation, eye redness, eye pruritus
Postmarketing reports: Eye discharge, eye swelling, erythema of eyelid, eyelid edema, increased lacrimation, blurred vision[Ref]

Nervous system

Frequency not reported: Headache
Postmarketing reports: Somnolence[Ref]


Frequency not reported: Nasopharyngitis[Ref]


1. "Product Information. Lastacaft (alcaftadine ophthalmic)." Vistakon, div of Johnson and Johnson Optical, Jacksonville, FL.

Some side effects of Lastacaft may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.