Ketorolac ophthalmic Side Effects
Commonly reported side effects of ketorolac ophthalmic include: burning sensation of eyes and stinging of eyes. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to ketorolac ophthalmic: ophthalmic solution
In addition to its needed effects, some unwanted effects may be caused by ketorolac ophthalmic. In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking ketorolac ophthalmic:More common:
- Itching, redness, tearing, or other sign of eye irritation not present before use of this medicine or becoming worse during use
- redness of the clear part of the eye
- sensitivity to light
- swelling of the eye
- throbbing pain
- Blurred vision or other change in vision
- eye irritation or redness
Some of the side effects that can occur with ketorolac ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Stinging or burning of the eye when medicine is applied
- Dry eyes
For Healthcare Professionals
Applies to ketorolac ophthalmic: ophthalmic solution
Ocular side effects have included transient burning and stinging upon instillation in 20% to 40% of patients. Conjunctival hyperemia, corneal infiltrates, and ocular edema have been reported in 1% to 5% of patients. Corneal edema, iritis, ocular inflammation, ocular irritation, ocular pain, superficial keratitis, and superficial ocular infections have been reported in 1% to 10% of patients. Corneal erosion, corneal thinning, and epithelial breakdown have also been reported.[Ref]
A 44-year-old female with a history of severe asthma was given ophthalmic ketorolac for the treatment of conjunctivitis previously unresponsive to topical antihistamine treatment. Two hours after instillation, she developed coughing and tightness in her chest which worsened over night. The next morning the patient was hospitalized with complaints of coughing, dyspnea at rest and wheezing. Her condition improved after administration of intravenous steroids and albuterol nebulizations.[Ref]
Hypersensitivity reactions have been reported in 1% to 10% of patients.[Ref]
1. Ostrov CS, Sirkin SR, Deutsch WE, Masi RJ, Chandler JW, Lindquist TD "Ketorolac, prednisolone, and dexamethasone for postoperative inflammation." Clin Ther 19 (1997): 259-72
2. "Product Information. Acular (ketorolac)." Allergan Inc, Irvine, CA.
3. "Product Information. Acular LS (ketorolac ophthalmic)." Allergan Inc, Irvine, CA.
4. Fraser-Smith EB, Matthews TR "Effect of ketorolac on Pseudomonas aeruginosa ocular infection in rabbits." J Ocul Pharmacol 4 (1988): 101-9
5. Flach AJ, Jampol LM, Weinberg D, Kraff MC, Yannuzzi LA, Campo RV, Neumann AC, Cupples HP, Lefler WH, Pulido JS, et al "Improvement in visual acuity in chronic aphakic and pseudophakic cystoid macular edema after treatment with topical 0.5% ketorolac tromethamine." Am J Ophthalmol 112 (1991): 514-9
6. Fraser-Smith EB, Matthews TR "Effect of ketorolac on herpes simplex virus type one ocular infection in rabbits." J Ocul Pharmacol 4 (1988): 321-6
7. Rooks WH 2d, Maloney PJ, Shott LD, Schuler ME, Sevelius H, Strosberg AM, Tanenbaum L, Tomolonis AJ, Wallach MB, Waterbury D, et al "The analgesic and anti-inflammatory profile of ketorolac and its tromethamine salt." Drugs Exp Clin Res 11 (1985): 479-92
8. Sitenga GL, Ing EB, Vandellen RG, Younge BR, Leavitt JA "Asthma caused by topical application of ketorolac." Ophthalmology 103 (1996): 890-2
Not all side effects for ketorolac ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about ketorolac ophthalmic
- Ketorolac drops
- Ketorolac tromethamine drops
- Ketorolac ophthalmic
- Ketorolac Ophthalmic (Advanced Reading)
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.