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Intropin Side Effects

Generic Name: dopamine

Note: This document contains side effect information about dopamine. Some of the dosage forms listed on this page may not apply to the brand name Intropin.

For the Consumer

Applies to dopamine: parenteral injection concentrate for iv infusion, parenteral injection for iv infusion

Side effects include:

Dopamine (the active ingredient contained in Intropin) may cause cardiac conduction abnormalities (e.g., ventricular arrhythmia, atrial fibrillation, widened QRS complex, ectopic heartbeats), tachycardia, angina, palpitation, bradycardia, vasoconstriction, hypotension, hypertension, dyspnea, nausea, vomiting, headache, anxiety, azotemia, piloerection, and gangrene of the extremities.

For Healthcare Professionals

Applies to dopamine: intravenous solution

Cardiovascular

Gangrene of the feet occurred in patients with preexisting vascular disorders and/or at doses of at least 10 to 14 mcg/kg/min given for prolonged periods of time.

Ventricular arrhythmias occurred at very high doses.[Ref]

Common (1% to 10%): Ectopic beats, tachycardia, anginal pain, palpitation, hypotension, vasoconstriction
Uncommon (0.1% to 1%): Aberrant ventricular conduction/ventricular arrhythmia, bradycardia, widened QRS complex, hypertension
Frequency not reported: Gangrene of the feet/extremities, peripheral cyanosis, fatal ventricular arrhythmias, atrial fibrillation, cardiac conduction abnormalities[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, vomiting[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]

Respiratory

Common (1% to 10%): Dyspnea[Ref]

Dermatologic

Very rare (less than 0.01%): Gangrene
Frequency not reported: Piloerection[Ref]

Local

Necrosis and tissue sloughing may be caused by extravasation of this drug.[Ref]

Frequency not reported: Necrosis, tissue sloughing, local ischemia and vasoconstriction[Ref]

Psychiatric

Frequency not reported: Anxiety[Ref]

Renal

Frequency not reported: Azotemia[Ref]

Ocular

Frequency not reported: Mydriasis[Ref]

Metabolic

Frequency not reported: Hypovolemia[Ref]

References

1. "Product Information. Intropin (dopamine)." DuPont Pharmaceuticals, Wilmington, DE.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Some side effects of Intropin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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