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Hylafem Side Effects

Generic Name: boric acid topical

Note: This document contains side effect information about boric acid topical. Some of the dosage forms listed on this page may not apply to the brand name Hylafem.

For the Consumer

Applies to boric acid topical: vaginal suppository

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • new or worsening symptoms (itch, vaginal discharge, etc);

  • vaginal burning sensation;

  • high fever; or

  • symptoms that go away and come back.

Common side effects may include:

  • watery vaginal discharge;

  • redness, mild burning; or

  • a gritty sensation in the vagina.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to boric acid topical: compounding powder, topical ointment, topical solution, vaginal suppository


Dermatologic side effects have included psoriasiform lesions, bullae and, intense erythematous eruptions, often covering the entire body and followed in one or two days by extensive desquamation. Mucus membranes are often involved.[Ref]


Gastrointestinal side effects have included vomiting, diarrhea, nausea, and epigastric pain.[Ref]

Nervous system

Nervous system side effects have included convulsions, delirium, and coma.[Ref]


Renal side effects have included acute tubular necrosis, oliguria and anuria.[Ref]


1. "Product Information. Boric Acid (boric acid topical)." Fougera, Melville, NY.

Some side effects of Hylafem may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.