Skip to Content

Hair Regrowth Treatment for Men Side Effects

Generic Name: minoxidil topical

Note: This page contains information about the side effects of minoxidil topical. Some of the dosage forms included on this document may not apply to the brand name Hair Regrowth Treatment for Men.

For the Consumer

Applies to minoxidil topical: topical foam, topical solution

In addition to its needed effects, some unwanted effects may be caused by minoxidil topical (the active ingredient contained in Hair Regrowth Treatment for Men). In the event that any of these side effects do occur, they may require medical attention.

Severity: Moderate

If any of the following side effects occur while taking minoxidil topical, check with your doctor or nurse as soon as possible:

Less common:
  • Itching or skin rash (continued)
  • Acne at site of application
  • burning of scalp
  • facial hair growth
  • increased hair loss
  • inflammation or soreness at root of hair
  • reddened skin
  • swelling of face
Signs and symptoms of too much medicine being absorbed into the body—Rare
  • Blurred vision or other changes in vision
  • chest pain
  • dizziness
  • fainting
  • fast or irregular heartbeat
  • flushing
  • headache
  • lightheadedness
  • numbness or tingling of hands, feet, or face
  • swelling of face, hands, feet, or lower legs
  • weight gain (rapid)

For Healthcare Professionals

Applies to minoxidil topical: topical foam, topical solution


Minoxidil topical (the active ingredient contained in Hair Regrowth Treatment for Men) is generally well tolerated. Dermatological adverse events are the only side effects reported more commonly as compared to placebo.[Ref]


Edema, salt and water retention, pericardial effusion, pericarditis, tamponade, tachycardia, and angina have been reported with oral minoxidil. Patients with underlying heart disease may be at increased risk for these or other cardiovascular adverse effects.[Ref]

Rarely, cardiovascular side effects have included edema, chest pain, blood pressure changes, palpitations, and changes in pulse rate with minoxidil topical therapy.[Ref]


Despite low levels of systemic absorption, in one study of 35 men using either topical minoxidil 2% twice a day or placebo for 6 months, minoxidil was associated with cardiac changes, such as significant increases in left ventricular end-diastolic volume, cardiac output, and left ventricular mass.[Ref]

Systemic side effects are uncommon since very little minoxidil is absorbed after topical application. In one study, the serum levels after 2.5 mg twice a day oral versus 2% twice a day topical minoxidil were 32.8 and 1.7 ng per mL, respectively.

Exacerbation of hair loss/alopecia has been reported.[Ref]


Rare cases of generalized hypertrichosis have been associated with topically applied minoxidil. Eczema, irritant dermatitis, and allergic contact dermatitis have also been reported.[Ref]


Nonspecific allergic reactions, hives, allergic rhinitis, facial swelling, and sensitivity to minoxidil topical (the active ingredient contained in Hair Regrowth Treatment for Men) have rarely been reported.[Ref]

Nervous system

Headache, dizziness, faintness, and light-headedness have been reported with minoxidil topical (the active ingredient contained in Hair Regrowth Treatment for Men) [Ref]


Diarrhea, nausea, and vomiting have been reported during treatment with minoxidil topical (the active ingredient contained in Hair Regrowth Treatment for Men) [Ref]


Visual disturbances, including decreased visual acuity, have been reported.[Ref]


1. "PDR Generics." Montvale, NJ: Medical Economics (1995):

Not all side effects for Hair Regrowth Treatment for Men may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about Hair Regrowth Treatment for Men (minoxidil topical)

Consumer resources

Other brands: Rogaine, Rogaine Women's, Rogaine Men's Extra Strength

Professional resources

Related treatment guides

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.