Gadoxetate disodium Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 15, 2024.

Applies to gadoxetate disodium: intravenous solution.

Serious side effects of Gadoxetate disodium

Along with its needed effects, gadoxetate disodium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking gadoxetate disodium:

Rare

• Blurred vision
• burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
• chest pain or tightness
• chills
• dizziness
• fainting
• fast, slow, or irregular heartbeat
• feeling hot
• headache
• inability to sit still
• need to keep moving
• nervousness
• pounding in the ears
• restlessness
• shakiness in the legs, arms, hands, or feet
• trembling or shaking of the hands or feet
• trouble breathing

Incidence not known

• Cold, clammy skin
• confusion
• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• fast, weak pulse
• lightheadedness
• restlessness
• sneezing
• stuffy or runny nose
• sweating
• unusual tiredness or weakness

Other side effects of Gadoxetate disodium

Some side effects of gadoxetate disodium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

• Back pain
• bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• change in sense of smell
• change in taste
• dry mouth
• feeling of constant movement of self or surroundings
• feeling of warmth
• general feeling of discomfort or illness
• increased sweating
• increased watering of the mouth
• itching
• loss of taste
• nausea
• rash with flat lesions or small raised lesions on the skin
• redness of the face, neck, arms, and occasionally, upper chest
• sensation of spinning
• vomiting

For Healthcare Professionals

Applies to gadoxetate disodium: intravenous solution.

Cardiovascular

Cardiovascular side effects have included chest pain, bundle branch block, increased blood pressure, and flushing.^[Ref]

Nervous system

Nervous system side effects have included headache, akathisia, dizziness, parosmia, vertigo, tremor, akathisia, and dysgeusia.^[Ref]

Respiratory

Respiratory side effects have included dyspnea and respiratory distress.^[Ref]

Gastrointestinal

Gastrointestinal side effects have included dry mouth, oral discomfort, salivary hypersecretion, nausea, and vomiting.^[Ref]

General

General side effects have included feeling hot, chills, discomfort, fatigue and malaise.^[Ref]

Dermatologic

Dermatologic side effects have included maculopapular rash, hyperhidrosis, rash, and pruritus.^[Ref]

Local

Local side effects have included injection site reactions (pain, burning, coldness, extravasation).^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer