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FML-S Liquifilm Side Effects

Generic Name: fluorometholone / sulfacetamide sodium ophthalmic

Note: This document contains side effect information about fluorometholone / sulfacetamide sodium ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name FML-S Liquifilm.

Applies to fluorometholone/sulfacetamide sodium ophthalmic: ophthalmic suspension


Ocular side effects associated with the fluorometholone component have included burning and stinging upon instillation, ocular irritation, visual disturbances, elevation of intraocular pressure with possible development of glaucoma, visual field defects, posterior subcapsular cataract formation, delayed wound healing, and optic nerve damage. Corticosteroid containing preparations have also been reported to cause acute anterior uveitis, perforation of the globe, keratitis, conjunctivitis, corneal ulcers, mydriasis, conjunctival hyperemia, loss of accommodation, and ptosis.

Local irritation, stinging, and burning have been reported with the use of sodium sulfacetamide.[Ref]


Fluorometholone ophthalmic has caused the development of secondary ocular infections.[Ref]


Hypersensitivity reactions to sodium sulfacetamide have been reported rarely. A case of Stevens Johnson syndrome has been reported in a patient who had previously experienced a bullous drug reaction to an orally administered sulfonamide. A case of local hypersensitivity which progressed to a fatal syndrome resembling systemic lupus erythematosus has also been reported.[Ref]


Gastrointestinal side effects have included taste perversion.[Ref]


Endocrine side effects have included rare cases of systemic hypercorticoidism after the use of topical steroids.[Ref]


1. "Product Information. Sulamyd Ophthalmic Solution (sodium sulfacetamide ophthalmic)." Schering Corporation, Kenilworth, NJ.

2. "Product Information. FML Ophthalmic Suspension (fluoromethalone ophthalmic)." Allergan Inc, Irvine, CA.

Some side effects of FML-S Liquifilm may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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