Fezolinetant Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 15, 2024.

Applies to fezolinetant: oral tablet.

Serious side effects of fezolinetant

Along with its needed effects, fezolinetant may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking fezolinetant:

Less common side effects

• dark urine
• feeling of warmth
• light-colored stools
• nausea
• redness of the face, neck, arms and occasionally, upper chest
• stomach pain
• sudden sweating
• vomiting
• yellow eyes or skin

Other side effects of fezolinetant

Some side effects of fezolinetant may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common side effects

• back pain
• diarrhea
• trouble sleeping

For healthcare professionals

Applies to fezolinetant: oral tablet.

General adverse events

The most common adverse effects occurring in 2% of patients or greater included abdominal pain, diarrhea, insomnia, back pain, hot flush, and hepatic transaminase elevations.^[Ref]

Cardiovascular

• Common (1% to 10%): Hot flush^[Ref]

Gastrointestinal

• Common (1% to 10%): Abdominal pain including upper and lower, diarrhea^[Ref]

Hepatic

• Common (1% to 10%): Transaminase elevations^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain^[Ref]

Psychiatric

• Common (1% to 10%): Insomnia^[Ref]

Further information

Fezolinetant side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer