Ethinyl Estradiol Side Effects
Medically reviewed by Drugs.com. Last updated on Jan 17, 2024.
Applies to ethinyl estradiol: compounding powder, oral tablet.
Cardiovascular adverse events
- Frequency not reported: Hypertension, thrombosis, thrombophlebitis, thromboembolism, myocardial infarction, stroke[Ref]
Dermatologic
- Frequency not reported: Erythema nodosum, erythema multiforme, vascular purpura, rash, chloasma[Ref]
Gastrointestinal
Genitourinary
- Frequency not reported: Intermenstrual bleeding, increase in the size of uterine fibromyomata, endometrial proliferation or aggravation of endometriosis, excessive production of cervical mucus, breast tenderness, breast pain, breast enlargement, breast secretion[Ref]
Hematologic
- Frequency not reported: Venous thromboembolism (e.g., deep leg or pelvic venous thrombosis)[Ref]
Hepatic
- Frequency not reported: Cholelithiasis, cholestatic jaundice[Ref]
Metabolic
- Frequency not reported: Sodium and water retention, reduced glucose tolerance, change in body weight, hypercalcemia, feminization in males, gynecomastia, testicular atrophy, male impotence[Ref]
Nervous system
Ocular
- Frequency not reported: Corneal discomfort (if contact lenses are used)[Ref]
Oncologic
- Frequency not reported: Endometrial neoplasia, endometrial cancer, breast cancer[Ref]
Psychiatric
- Frequency not reported: Mood changes (e.g., elation, depression), probable dementia[Ref]
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References
1. Cerner Multum, Inc. "UK Summary of Product Characteristics."
Frequently asked questions
More about ethinyl estradiol
- Check interactions
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: estrogens
- Breastfeeding
Patient resources
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Further information
Ethinyl estradiol side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.
