Ethinyl estradiol Side Effects
Medically reviewed by Drugs.com. Last updated on Aug 31, 2023.
Applies to ethinyl estradiol: compounding powder, oral tablet.
Cardiovascular
Frequency not reported: Hypertension, thrombosis, thrombophlebitis, thromboembolism, myocardial infarction, stroke[Ref]
Dermatologic
Frequency not reported: Erythema nodosum, erythema multiforme, vascular purpura, rash, chloasma[Ref]
Gastrointestinal
Frequency not reported: Nausea, vomiting[Ref]
Genitourinary
Frequency not reported: Intermenstrual bleeding, increase in the size of uterine fibromyomata, endometrial proliferation or aggravation of endometriosis, excessive production of cervical mucus, breast tenderness, breast pain, breast enlargement, breast secretion[Ref]
Hematologic
Frequency not reported: Venous thromboembolism (e.g., deep leg or pelvic venous thrombosis)[Ref]
Hepatic
Frequency not reported: Cholelithiasis, cholestatic jaundice[Ref]
Metabolic
Frequency not reported: Sodium and water retention, reduced glucose tolerance, change in body weight, hypercalcemia, feminization in males, gynecomastia, testicular atrophy, male impotence[Ref]
Nervous system
Frequency not reported: Headache, migraine, dizziness[Ref]
Ocular
Frequency not reported: Corneal discomfort (if contact lenses are used)[Ref]
Oncologic
Frequency not reported: Endometrial neoplasia, endometrial cancer, breast cancer[Ref]
Psychiatric
Frequency not reported: Mood changes (e.g., elation, depression), probable dementia[Ref]
Frequently asked questions
More about ethinyl estradiol
- Check interactions
- Compare alternatives
- Dosage information
- During pregnancy
- Drug class: estrogens
- Breastfeeding
Patient resources
Related treatment guides
References
1. Cerner Multum, Inc. UK Summary of Product Characteristics.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
