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Ethinyl Estradiol Dosage

Applies to the following strengths: 0.02 mg; 0.05 mg; 0.5 mg

Usual Adult Dose for Postmenopausal Symptoms

10 to 50 mcg orally once a day

-Given on a cyclical basis, 3 weeks on and 1 week off.
-Addition of progestogen is not recommended in women without a uterus who did not have endometriosis.
-A progestogen should be added for at least 12 to 14 days every month (28-day cycle) in women with a uterus (or in endometriosis when endometrial foci are present despite hysterectomy).
-Start therapy any time in women with amenorrhea.
-Start therapy on the first day of bleeding in women who are menstruating.

Use: For postmenopausal symptoms due to estrogen deficiency (including prevention of postmenopausal osteoporosis)

Usual Adult Dose for Prostate Cancer

0.15 to 1.5 mg orally once a day

Use: Palliative treatment of prostatic cancer

Usual Adult Dose for Primary Ovarian Failure

10 to 50 mcg orally once a day

-Usually given on a cyclical basis.
-Follow initial estrogen by combined estrogen/progestogen.

Use: Hormone replacement therapy (HRT) for failure of ovarian development (e.g., in patients with gonadal dysgenesis where initial estrogen therapy is later followed by combined estrogen/progestogen therapy)

Usual Adult Dose for Menstrual Disorders

20 to 50 mcg orally once a day from day 5 to day 25 of each cycle

-A progestogen is given daily throughout the cycle or from days 15 to 25 of the cycle.
-Take a missed dose as soon as it is remembered; if it is nearly time for the next dose then the patient should wait until then. Two doses should not be taken together. Forgetting a dose may increase the likelihood of break-through bleeding and spotting.

Use: For disorders of menstruation (given in conjunction with a progestogen)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

This drug is contraindicated in acute liver disease or a history of liver disease as long as liver function tests have failed to return to normal.


Data not available

Other Comments

Administration advice:
-A missed dose should be taken as soon as remembered. The missed dose should be skipped if it is almost time for the next scheduled dose.

Patient advice:
-Forgetting a dose may increase the chances of breakthrough bleeding
-See your doctor for regular check ups
-Check your breasts regularly for any changes
-Go for regular breast screening and cervical smear tests

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.