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Eovist Side Effects

Generic Name: gadoxetate disodium

Note: This document contains side effect information about gadoxetate disodium. Some of the dosage forms listed on this page may not apply to the brand name Eovist.

For the Consumer

Applies to gadoxetate disodium: intravenous solution

Along with its needed effects, gadoxetate disodium (the active ingredient contained in Eovist) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking gadoxetate disodium:

  • Blurred vision
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain
  • chills
  • difficult or labored breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • feeling hot
  • headache
  • inability to sit still
  • need to keep moving
  • nervousness
  • pounding in the ears
  • restlessness
  • shakiness in the legs, arms, hands, or feet
  • tightness in the chest
  • trembling or shaking of the hands or feet
  • troubled breathing
Incidence not known
  • Cold, clammy skin
  • confusion
  • fast, weak pulse
  • lightheadedness
  • restlessness
  • sweating

Some side effects of gadoxetate disodium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Back pain
  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • change in sense of smell
  • change in taste
  • dry mouth
  • feeling of constant movement of self or surroundings
  • feeling of warmth
  • general feeling of discomfort or illness
  • increased sweating
  • increased watering of the mouth
  • itching
  • loss of taste
  • nausea
  • rash with flat lesions or small raised lesions on the skin
  • redness of the face, neck, arms, and occasionally, upper chest
  • sensation of spinning
  • unusual tiredness or weakness
  • vomiting

For Healthcare Professionals

Applies to gadoxetate disodium: intravenous solution


Cardiovascular side effects have included chest pain, bundle branch block, increased blood pressure, and flushing.[Ref]

Nervous system

Nervous system side effects have included headache, akathisia, dizziness, parosmia, vertigo, tremor, akathisia, and dysgeusia.[Ref]


Respiratory side effects have included dyspnea and respiratory distress.[Ref]


Gastrointestinal side effects have included dry mouth, oral discomfort, salivary hypersecretion, nausea, and vomiting.[Ref]


General side effects have included feeling hot, chills, discomfort, fatigue and malaise.[Ref]


Dermatologic side effects have included maculopapular rash, hyperhidrosis, rash, and pruritus.[Ref]


Local side effects have included injection site reactions (pain, burning, coldness, extravasation).[Ref]


1. "Product Information. Eovist (gadoxetate)." Bayer Pharmaceutical Inc, West Haven, CT.

Some side effects of Eovist may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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