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Empliciti Side Effects

Generic name: elotuzumab

Medically reviewed by Drugs.com. Last updated on Aug 28, 2024.

Note: This document provides detailed information about Empliciti.

Applies to elotuzumab: intravenous powder for solution Side Effects associated with elotuzumab. Some dosage forms listed on this page may not apply specifically to the brand name Empliciti.

Applies to elotuzumab: intravenous powder for solution.

Precautions

It is very important that your doctor check you at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine together with lenalidomide and dexamethasone or pomalidomide and dexamethasone while you are pregnant can harm your unborn baby. Men and women should use an effective form of birth control to prevent pregnancy during treatment with this medicine. If you think you have become pregnant while receiving the medicine, tell your doctor right away.

Infusion reactions may occur with this medicine. Tell your doctor right away if you have a skin rash, dizziness, fever or chills, headache, nausea or vomiting, slow or fast heartbeat, lightheadedness or fainting, sweating, or unusual tiredness or weakness.

Call your doctor right away if you have a cough that would not go away, weight loss, night sweats, fever, chills, or flu-like symptoms, such as a runny or stuffy nose, headache, or blurred vision. These may be symptoms of an infection.

Using this medicine may increase your risk of getting other types of cancer (including skin cancer). Talk to your doctor if you have concerns about this risk.

Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.

Before you have any medical tests, tell the medical doctor in charge that you are receiving this medicine. The results of some tests may be affected by this medicine.

Serious side effects of Empliciti

Along with its needed effects, elotuzumab (the active ingredient contained in Empliciti) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking elotuzumab:

More common side effects

  • blurred vision
  • body aches or pain
  • chest pain
  • chills
  • clay-colored stools
  • confusion
  • cough
  • dark urine
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • ear congestion
  • fever
  • headache
  • hives, itching, skin rash
  • hoarseness
  • irritation
  • joint pain, stiffness, or swelling
  • loss of appetite
  • loss of voice
  • lower back or side pain
  • nasal congestion
  • nausea
  • nervousness
  • painful or difficult urination
  • persistent sore that does not heal
  • pink skin growth
  • pounding in the ears
  • reddish patch or irritated area
  • redness of the skin
  • runny nose
  • shiny skin bump
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • stomach pain or tenderness
  • stuffy nose
  • sweating
  • swelling of the eyelids, face, lips, hands, or feet
  • tightness in the chest
  • troubled breathing or swallowing
  • unusual tiredness or weakness
  • vomiting
  • white, yellow or waxy scar-like area on the skin
  • yellow eyes or skin

Less common side effects

  • agitation
  • anxiety
  • decreased awareness or responsiveness
  • decreased urine output
  • depression
  • dizziness or lightheadedness
  • fainting
  • fast heartbeat
  • hostility
  • irritability
  • loss of consciousness
  • muscle twitching
  • pale skin
  • rapid weight gain
  • seizures
  • severe sleepiness
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual drowsiness, dullness, or feeling of sluggishness

Other side effects of Empliciti

Some side effects of elotuzumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • blindness
  • burning, numbness, tingling, or painful sensations
  • decreased appetite
  • decreased vision
  • decreased weight
  • diarrhea
  • difficulty having a bowel movement
  • muscle aches
  • night sweats
  • pain in the arms or legs
  • unsteadiness or awkwardness
  • weakness in the arms, hands, legs, or feet

For healthcare professionals

Applies to elotuzumab: intravenous powder for injection.

Dermatologic adverse events

Gastrointestinal

Hematologic

Hepatic

Hypersensitivity

Metabolic

Musculoskeletal

Nervous system

Ocular

Oncologic

Other

Psychiatric

Renal

Respiratory

Immunologic

Local

See also:

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2015) "Product Information. Empliciti (elotuzumab)." Bristol-Myers Squibb

Frequently asked questions

Further information

Empliciti side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.