Skip to Content

Dutasteride / tamsulosin Side Effects

For the Consumer

Applies to dutasteride / tamsulosin: oral capsule

Along with its needed effects, dutasteride/tamsulosin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking dutasteride / tamsulosin:

More common
  • Chills
  • cold sweats
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
Less common
  • Chest pain
  • cough or hoarseness
  • fever
  • lower back or side pain
  • painful or difficult urination
Incidence not known
  • Blistering, flaking, or peeling of the skin
  • blurred vision
  • difficulty with breathing
  • fast, irregular, pounding, or racing heartbeat or pulse
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • pain or swelling of the treated skin
  • painful or prolonged erection of the penis
  • shortness of breath
  • sweating
  • unusual tiredness or weakness

Some side effects of dutasteride / tamsulosin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Change or problem with discharge of semen
  • decreased interest in sexual intercourse
  • dizziness
  • enlarged and painful breasts
  • inability to have or keep an erection
  • loss in sexual ability, desire, drive, or performance
Less common
  • Back pain
  • body aches or pain
  • congestion
  • diarrhea
  • dryness or soreness of the throat
  • headache
  • increased cough
  • lack or loss of strength
  • pain or tenderness around the eyes and cheekbones
  • runny nose
  • shortness of breath or troubled breathing
  • sleepiness or unusual drowsiness
  • sleeplessness
  • sneezing
  • stuffy nose
  • tender, swollen glands in the neck
  • tightness of the chest or wheezing
  • trouble sleeping
  • trouble with swallowing
  • unable to sleep
  • voice changes
Incidence not known

For Healthcare Professionals

Applies to dutasteride / tamsulosin: oral capsule


The most common adverse reactions were ejaculation disorders, impotence, decreased libido, breast disorders, and dizziness.[Ref]


Very common (10% or more): Ejaculation disorders (up to 11%)
Common (1% to 10%): Impotence

Common (1% to 10%): Ejaculation disorders, impotence
Postmarketing reports: Testicular pain, testicular swelling

Common (1% to 10%): Ejaculation disorders, impotence
Postmarketing reports: Priapism[Ref]


Common (1% to 10%): Libido decreased

Common (1% to 10%): Libido decreased
Postmarketing reports: Depressed mood

Common (1% to 10%): Libido decreased, insomnia[Ref]


Common (1% to 10%): Breast disorders

Common (1% to 10%): Breast disorders
Postmarketing reports: Localized edema

Common (1% to 10%): Asthenia, chest pain
Uncommon (0.1% to 1%): Breast disorders[Ref]

Nervous system

Common (1% to 10%): Dizziness

Uncommon (0.1% to 1%): Dizziness

Common (1% to 10%): Somnolence
Uncommon (0.1% to 1%): Dizziness[Ref]


Uncommon (0.1% to 1%): Cardiac failure

Uncommon (0.1% to 1%): Cardiac failure

Very common (10% or more): Orthostatic hypotension (up to 16%)
Uncommon (0.1% to 1%): Cardiac failure
Postmarketing reports: Palpitations, atrial fibrillation, arrhythmia, tachycardia, hypotension[Ref]


Postmarketing reports: Hypersensitivity reactions

Common (1% to 10%): Infection
Postmarketing reports: Hypersensitivity reactions[Ref]


Common (1% to 10%): Gleason score 8 to 10 prostate cancer
Frequency not reported: Male breast cancer[Ref]


Common (1% to 10%): Rhinitis, pharyngitis, cough increased, sinusitis
Postmarketing reports: Respiratory problems, dyspnea, epistaxis[Ref]


Common (1% to 10%): Diarrhea
Postmarketing reports: Constipation, vomiting, dry mouth[Ref]


Common (1% to 10%): Back pain[Ref]


Postmarketing reports: Rash, pruritus, urticaria, serious skin reactions, angioedema

Postmarketing reports: Rash, urticaria, pruritus, angioedema, skin desquamation, Stevens-Johnson syndrome, erythema multiforme, dermatitis exfoliative[Ref]


Postmarketing reports: Blurred vision, visual impairment[Ref]


1. "Product Information. Jalyn (dutasteride-tamsulosin)." GlaxoSmithKline, Research Triangle Park, NC.

Some side effects of dutasteride / tamsulosin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.