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Dried Factor VIII Fraction Type 8Y Side Effects

Generic Name: antihemophilic factor / von willebrand factor

Note: This document contains side effect information about antihemophilic factor / von willebrand factor. Some of the dosage forms listed on this page may not apply to the brand name Dried Factor VIII Fraction Type 8Y.

For the Consumer

Applies to antihemophilic factor / von willebrand factor: intravenous powder for solution

Along with its needed effects, antihemophilic factor/von willebrand factor may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking antihemophilic factor / von willebrand factor:

More common Incidence not known

For Healthcare Professionals

Applies to antihemophilic factor / von willebrand factor: intravenous powder for injection


The most serious side effects were anaphylaxis/hypersensitivity reactions.[Ref]


Common (1% to 10%): Allergy, infection, hypersensitivity
Uncommon (0.1% to 1%): Factor VIII inhibition
Very rare (less than 0.01%): Von Willebrand factor inhibition, anaphylactic shock
Frequency not reported: Allergic-anaphylactic reactions, sepsis[Ref]


Very common (10% or more): Pain (up to 17.5%)
Common (1% to 10%): Fever, surgery, facial edema, chest pain, peripheral edema, rigors
Frequency not reported: Chills, pseudothrombocytopenia, postoperative pain
Postmarketing reports: Fatigue, malaise[Ref]


Very common (10% or more): Nausea (up to 23.8%), constipation (11.1%)
Common (1% to 10%): Gastrointestinal bleeding, abdominal pain, vomiting
Frequency not reported: Postoperative nausea[Ref]


Common (1% to 10%): Groin bleed, ear bleed, shoulder bleed, anemia/hemoglobin decreased, thromboembolic event
Frequency not reported: Hemorrhage, hematocrit decreased, postoperative hemorrhage, postoperative wound bleeding
Postmarketing reports: Hemolysis[Ref]

Nervous system

Common (1% to 10%): Cerebral hemorrhage/subdural hematoma, dizziness, headache, dysgeusia, somnolence
Frequency not reported: Headache, paresthesia, drowsiness[Ref]


Common (1% to 10%): Epistaxis, hemoptysis, pulmonary embolus, sore throat
Frequency not reported: Respiratory distress
Postmarketing reports: Dyspnea, cough, sneezing, throat irritation[Ref]


Common (1% to 10%): Sweating increased, pruritus, rash, urticaria[Ref]


Common (1% to 10%): Menorrhagia, hematuria, urinary retention, urinary tract infection[Ref]


Common (1% to 10%): ALT increased, liver function test abnormal[Ref]


Common (1% to 10%): Back pain, muscle and joint stiffness
Frequency not reported: Extremity pain
Postmarketing reports: Joint pain[Ref]


Common (1% to 10%): Thrombophlebitis
Frequency not reported: Orthostatic hypotension, phlebitis, vasodilation, bradycardia, palpitations[Ref]


Common (1% to 10%): Infusion site erythema or rash or pain
Frequency not reported: Injection site bleeding
Postmarketing reports: Infusion site pain[Ref]


Common (1% to 10%): Insomnia[Ref]


Frequency not reported: Blurred vision[Ref]


Frequency not reported: Pyelonephritis[Ref]


Postmarketing reports: Hypervolemia[Ref]


1. Cerner Multum, Inc. "Australian Product Information." O 0

2. "Product Information. Alphanate (antihemophilic factor-von Willebrand factor)." Alpha Therapeutic Corporation, Los Angeles, CA.

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

4. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.

5. "Product Information. Wilate (antihemophilic factor-von Willebrand factor)." Octapharma USA, Centreville, VA.

Some side effects of Dried Factor VIII Fraction Type 8Y may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

More about Dried Factor VIII Fraction Type 8Y (antihemophilic factor / von willebrand factor)

Consumer resources

Other brands: Alphanate, Humate-P, Wilate

Professional resources

Related treatment guides

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