Skip to Content

Antihemophilic factor / von willebrand factor Pregnancy and Breastfeeding Warnings

Antihemophilic factor / von willebrand factor is also known as: Alphanate, Dried Factor VIII Fraction Type 8Y, Haemate P, Humate-P, Optivate, Wilate, Wilstart

Medically reviewed on January 30, 2017

Antihemophilic factor / von willebrand factor Pregnancy Warnings

Safety has not been established during pregnancy; use only if clearly needed.

AU TGA pregnancy category: Not formally assigned to a pregnancy category.
US FDA pregnancy category: C

There are no controlled data in human pregnancy.

Delivery confers an increased risk of hemorrhagic events in patients with von Willebrand disease.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Antihemophilic factor / von willebrand factor Breastfeeding Warnings

AU and UK: Safety has not been established; use only if clearly needed.
US: Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.
  2. "Product Information. Wilate (antihemophilic factor-von Willebrand factor)." Octapharma USA, Centreville, VA.
  3. Cerner Multum, Inc. "Australian Product Information." O 0
  4. "Product Information. Alphanate (antihemophilic factor-von Willebrand factor)." Alpha Therapeutic Corporation, Los Angeles, CA.
  5. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

References for breastfeeding information

  1. "Product Information. Wilate (antihemophilic factor-von Willebrand factor)." Octapharma USA, Centreville, VA.
  2. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring, King of Prussia, PA.
  3. Cerner Multum, Inc. "Australian Product Information." O 0
  4. "Product Information. Alphanate (antihemophilic factor-von Willebrand factor)." Alpha Therapeutic Corporation, Los Angeles, CA.
  5. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide