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Antihemophilic factor/von willebrand factor Pregnancy and Breastfeeding Warnings

Medically reviewed by Drugs.com. Last updated on Jan 20, 2023.

Antihemophilic factor/von willebrand factor is also known as: Alphanate, Dried Factor VIII Fraction Type 8Y, Haemate P, Humate-P, Optivate, Wilate, Wilstart

Antihemophilic factor/von willebrand factor Pregnancy Warnings

Safety has not been established during pregnancy; use only if clearly needed.

AU TGA pregnancy category: Not formally assigned to a pregnancy category.
US FDA pregnancy category: C

There are no controlled data in human pregnancy.

Delivery confers an increased risk of hemorrhagic events in patients with von Willebrand disease.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Antihemophilic factor/von willebrand factor Breastfeeding Warnings

AU and UK: Safety has not been established; use only if clearly needed.
US: Caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments: The effects in the nursing infant are unknown.

See references

See also

References for pregnancy information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. Cerner Multum, Inc. "Australian Product Information." O 0
  3. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring LLC (2022):
  4. "Product Information. Wilate (antihemophilic factor-von Willebrand factor)." Octapharma USA (2022):
  5. "Product Information. Alphanate (antihemophilic factor-von Willebrand factor)." Alpha Therapeutic Corporation (2022):

References for breastfeeding information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. Cerner Multum, Inc. "Australian Product Information." O 0
  3. "Product Information. Humate-P (antihemophilic factor-von Willebrand factor)." CSL Behring LLC (2022):
  4. "Product Information. Wilate (antihemophilic factor-von Willebrand factor)." Octapharma USA (2022):
  5. "Product Information. Alphanate (antihemophilic factor-von Willebrand factor)." Alpha Therapeutic Corporation (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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