Skip to main content

Doxylamine / phenylephrine Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 27, 2022.

Applies to doxylamine / phenylephrine: oral tablet.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use this medicine only to make a child sleepy.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe dizziness;

  • nervousness, trouble sleeping;

  • little or no urination; or

  • high blood pressure (severe headache, pounding in your neck or ears).

Common side effects may include:

  • dizziness, drowsiness;

  • dry mouth, nose, or throat;

  • constipation;

  • blurred vision; or

  • feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.