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Doxapram Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 11, 2024.

Applies to doxapram: parenteral injection.

Side effects include:

Cough, dyspnea, tachypnea, headache, dizziness, apprehension, hypertension, flushing, sweating, nausea, vomiting, diarrhea, urinary retention, muscle spasticity.

For healthcare professionals

Applies to doxapram: intravenous solution.

General adverse events

In preterm neonates and infants, this drug has caused significant QT interval prolongation (associated with atrioventricular block in some cases), bloody stools, abdominal distension, necrotizing enterocolitis, multiple gastric perforations/increased gastric residuals, neurodevelopmental delay, vomiting, premature teeth eruption, hypertension, irritability, jitteriness, hyperglycemia, glucosuria, erratic limb movements, excessive crying, and disturbed sleep.

Seizures have occurred in premature neonates with risk factors such as a previous seizure, perinatal asphyxia, or intracerebral hemorrhage. In many cases, this drug was given following administration of xanthine derivatives (e.g., caffeine, aminophylline, or theophylline).[Ref]

Cardiovascular

Dermatologic

Gastrointestinal

Genitourinary

Hematologic

Musculoskeletal

Nervous system

Ocular

Other

Psychiatric

Respiratory

References

1. (2001) "Product Information. Dopram (doxapram)." West Ward Pharmaceutical Corporation

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Further information

Doxapram side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.