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Dexacidin Side Effects

Generic name: dexamethasone / neomycin / polymyxin b ophthalmic

Medically reviewed by Last updated on Apr 6, 2024.

Note: This document contains side effect information about dexamethasone / neomycin / polymyxin b ophthalmic. Some dosage forms listed on this page may not apply to the brand name Dexacidin.

Applies to dexamethasone/neomycin/polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension.

Serious side effects of Dexacidin

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Other side effects of Dexacidin

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

For Healthcare Professionals

Applies to dexamethasone/neomycin/polymyxin b ophthalmic: ophthalmic ointment, ophthalmic suspension.


The most frequently reported side effects were ocular discomfort, keratitis, eye irritation, and allergic sensitization.[Ref]


Uncommon (0.1% to 1%): Keratitis, intraocular pressure increased, vision blurred, photophobia, mydriasis, eyelid ptosis, eye pain, eye swelling, eye pruritus, ocular discomfort, foreign body sensation, eye irritation, ocular hyperemia, lacrimation increased

Frequency not reported: Corneal thinning, ulcerative keratitis


Frequency not reported: Intraocular pressure increased, glaucoma, visual acuity reduced, visual field defect, posterior subcapsular cataract formation, globe perforation, keratitis, conjunctivitis, corneal ulcer, conjunctival hyperemia, optic nerve damage, wound healing delayed[Ref]


Uncommon (0.1% to 1%): Hypersensitivity

Frequency not reported: Allergic sensitization[Ref]

Nervous system

Frequency not reported: Headache[Ref]


Frequency not reported: Secondary ocular infection developed, fungal infection developed[Ref]


Frequency not reported: Stevens-Johnson syndrome


1. "Product Information. Maxitrol (dexamethasone/neomycin/polymyxin B ophthalmic)." Alcon Laboratories Inc

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.