Desirudin Side Effects
For the Consumer
Applies to desirudin: parenteral powder for injection
Side effects include:
Hemorrhage, including hematoma, was most common adverse effect in clinical studies in patients undergoing elective total hip-replacement surgery.
For Healthcare Professionals
Applies to desirudin: subcutaneous powder for injection
General
The most common adverse reaction was hemorrhage.[Ref]
Cardiovascular
Very common (10% or more): Any hemorrhage (30%)
Common (1% to 10%): Serious hemorrhage, deep vein thrombosis
Uncommon (0.1% to 1%): Major hemorrhage
Frequency not reported: Thrombosis, hypotension
Postmarketing reports: Fatal hemorrhage[Ref]
Other
Common (1% to 10%): Wound secretion
Frequency not reported: Leg edema, fever, healing impaired[Ref]
Gastrointestinal
Common (1% to 10%): Nausea
Frequency not reported: Vomiting, hematemesis[Ref]
Hematologic
Common (1% to 10%): Anemia
Frequency not reported: Hemoglobin decreased[Ref]
Dermatologic
Common (1% to 10%): Irritative skin reactions[Ref]
Local
Common (1% to 10%): Injection site mass[Ref]
Immunologic
Frequency not reported: Allergic reaction, anti-hirudin antibodies
Postmarketing reports: Anaphylactic/anaphylactoid reaction[Ref]
Nervous system
Frequency not reported: Dizziness, cerebrovascular disorder[Ref]
Genitourinary
Frequency not reported: Hematuria[Ref]
Musculoskeletal
Frequency not reported: Leg pain[Ref]
Respiratory
Frequency not reported: Epistaxis[Ref]
References
1. "Product Information. Ipravask (desirudin)." Aventis Pharmaceuticals, Swiftwater, PA.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about desirudin
Consumer resources
Other brands: Iprivask
