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Desirudin Side Effects

Medically reviewed by Drugs.com. Last updated on Mar 11, 2024.

Applies to desirudin: subcutaneous powder for injection.

Important warnings This medicine can cause some serious health issues

You should not use this medicine if you have active or uncontrolled bleeding, or an irreversible blood clotting disorder.

Desirudin can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), especially if you are also using other drugs that can affect blood clotting, including blood thinners or NSAIDs (ibuprofen, Advil, Aleve, and others). This type of blood clot can lead to long-term or permanent paralysis.

Get emergency medical help if you have symptoms of a spinal cord blood clot such as back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Also seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Call your doctor at once if you have:

Serious side effects may be more likely in adults who are 75 years or older.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to desirudin: subcutaneous powder for injection.

General

The most common adverse reaction was hemorrhage.[Ref]

Cardiovascular

Other

Gastrointestinal

Hematologic

Dermatologic

Local

Immunologic

Nervous system

Genitourinary

Musculoskeletal

Respiratory

References

1. (2003) "Product Information. Ipravask (desirudin)." Aventis Pharmaceuticals

Further information

Desirudin side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.