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Thrombin inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Thrombin inhibitors are anticoagulants that bind to and inhibit the activity of thrombin therefore prevent blood clot formation. Thrombin inhibitors inactivate free thrombin and also the thrombin that is bound to fibrin. Thrombin has many important functions in the clotting pathway, so it is a good target for anticoagulants drugs.

Thrombin inhibitors are used to prevent arterial and venous thrombosis. They can be used to prevent and treat deep vein thrombosis, or used as prophylaxis in atrial fibrillation to avoid thromboembolism.

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