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Cromolyn ophthalmic Side Effects

For the Consumer

Applies to cromolyn ophthalmic: ophthalmic solution

Along with its needed effects, cromolyn ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking cromolyn ophthalmic:

  • Rash or redness around the eyes
  • swelling of the membrane covering the white part of the eye, redness of the white part of the eye, styes, or other eye irritation not present before therapy

Some side effects of cromolyn ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning or stinging of eye (mild and temporary)
Less common or rare
  • Dryness or puffiness around the eye
  • watering or itching of eye (increased)

For Healthcare Professionals

Applies to cromolyn ophthalmic: ophthalmic solution


The most commonly reported side effect includes eye irritation such as burning/stinging.[Ref]


Uncommon: Conjunctival infection; watery eyes, itchy eyes, dryness around the eye, puffy eyes, eye irritation, styes, swelling of the eyelids, conjunctiva swelling[Ref]

Swelling of the eyelids or the conjunctiva has been reported and is thought to be due to a hypersensitivity to the preservative, benzalkonium chloride.[Ref]


Rare: Immediate hypersensitivity reactions including edema, rash, dyspnea[Ref]


1. "Product Information. Cromolyn Sodium Ophthalmic (cromolyn ophthalmic (sodium cromoglycate ophthalmic))." Akorn Inc, Buffalo Grove, IL.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

Some side effects of cromolyn ophthalmic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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