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Cosyntropin Side Effects

For the Consumer

Applies to cosyntropin: injection solution reconstituted

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
  • Fast or slow heartbeat.
  • Swelling in the arms or legs.

What are some other side effects of this drug?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to cosyntropin: injectable powder for injection, intravenous solution

Cardiovascular

Cardiovascular side effects have included bradycardia, tachycardia and hypertension.[Ref]

Dermatologic

Dermatologic side effects have included rash and slight whealing with splotchy erythema at the injection site.[Ref]

General

General side effects have included peripheral edema.[Ref]

Hypersensitivity

Hypersensitivity side effects have rarely included anaphylaxis.[Ref]

Patients with a preexisting allergic disease and/or a previous reaction to natural ACTH may experience a rare hypersensitivity reaction to cosyntropin.[Ref]

References

1. "Product Information. Cortrosyn (cosyntropin)" Organon, West Orange, NJ.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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