Conjugated Estrogens / Methyltestosterone Side Effects

Applies to conjugated estrogens / methyltestosterone: oral tablet.

Important warnings This medicine can cause some serious health issues

Conjugated estrogens increase the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus.

Taking progestins, another hormone drug, with conjugated estrogens may lower the risk of developing this condition.

Therefore, if your uterus has not been removed, your doctor may prescribe a progestin for you to take together with the estrogen.

Visit your doctor regularly and report any unusual vaginal bleeding right away.

Have yearly physical exams and examine your breasts for lumps on a monthly basis.

Notify your doctor if you experience vomiting, swelling of the arms or legs, hoarseness, deepening of the voice, male-pattern baldness, excessive hair growth, clitoral enlargement, or yellowing of the skin or eyes.

Do not take conjugated estrogens and methyltestosterone if you are pregnant.

If you experience any of the following serious side effects, stop taking conjugated estrogens and methyltestosterone and seek emergency medical attention or notify your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

• a blood clot (pain, redness, and swelling in an arm or leg; shortness of breath; chest pain; headache; blurred vision; or confusion);

• a lump in a breast;

• liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or

• hoarseness, deepening of the voice, male-pattern baldness, excessive hair growth, or clitoral enlargement (these changes may be irreversible).

Other, less serious side effects may be more likely to occur. Continue to take the medication and talk to your doctor if you experience

• decreased appetite or nausea;

• swollen breasts;

• acne or skin color changes;

• increased or decreased sex drive;

• migraine headaches or dizziness;

• water retention (swollen hands, feet, or ankles);

• intolerance to contact lenses;

• depression; or

• changes in menstrual cycle or breakthrough bleeding.

Conjugated estrogens increase the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus. Taking progestins, another hormone drug, with conjugated estrogens may lower the risk of developing this condition. Therefore, if your uterus has not been removed, your doctor may prescribe a progestin for you to take together with the estrogen. Visit your doctor regularly and report any unusual vaginal bleeding right away.

It is unclear to what extent estrogen treatments may affect the risk of breast cancer.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Further information

Conjugated estrogens/methyltestosterone side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer