Bacitracin / hydrocortisone / neomycin / polymyxin b topical Side Effects
For the Consumer
Applies to bacitracin / hydrocortisone / neomycin / polymyxin b topical: external ointment
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad skin irritation.
- Skin changes (pimples, stretch marks, slow healing, hair growth).
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Skin irritation.
- Dry skin.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to bacitracin / hydrocortisone / neomycin / polymyxin b topical: topical ointment
Hypersensitivity side effects associated with neomycin have included contact sensitization characterized by itching and swelling in 0.9% to 1% of patients.[Ref]
Nervous system side effects associated with neomycin have included ototoxicity.[Ref]
Renal side effects associated with neomycin have included nephrotoxicity.[Ref]
Dermatologic side effects associated with the use of topical corticosteroids have included burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. These reactions are more likely with the use of occlusive dressings or with use over prolonged periods of time.[Ref]
Endocrine side effects of topical corticosteroids are rare. Glucose intolerance and hyperglycemia may be induced by corticosteroids. These drugs can rarely suppress the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.[Ref]
1. "Product Information. Cortisporin Topical (hydrocortisone/neomycin/polymyxin B topical)." Monarch Pharmaceuticals Inc, Bristol, TN.
2. "Product Information. Cortisporin (bacitracin/HC/neomycin/polymyxin B topical)." Monarch Pharmaceuticals Inc, Bristol, TN.
Some side effects of bacitracin / hydrocortisone / neomycin / polymyxin b topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
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