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Bacitracin / hydrocortisone / neomycin / polymyxin b topical Side Effects

For the Consumer

Applies to bacitracin / hydrocortisone / neomycin / polymyxin b topical: ointment

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning, dryness, or itching of skin; worsening of condition.

Seek medical attention right away if any of these SEVERE side effects occur while taking bacitracin / hydrocortisone / neomycin / polymyxin b topical:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); hearing or kidney problems; second infection.

For Healthcare Professionals

Applies to bacitracin / hydrocortisone / neomycin / polymyxin b topical: topical ointment

Hypersensitivity

Hypersensitivity side effects associated with neomycin have included contact sensitization characterized by itching and swelling in 0.9% to 1% of patients.[Ref]

Nervous system

Nervous system side effects associated with neomycin have included ototoxicity.[Ref]

Renal

Renal side effects associated with neomycin have included nephrotoxicity.[Ref]

Dermatologic

Dermatologic side effects associated with the use of topical corticosteroids have included burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. These reactions are more likely with the use of occlusive dressings or with use over prolonged periods of time.[Ref]

Endocrine

Endocrine side effects of topical corticosteroids are rare. Glucose intolerance and hyperglycemia may be induced by corticosteroids. These drugs can rarely suppress the hypothalamic-pituitary-adrenal axis. This suppression is more likely when higher potency topical steroids are used over extensive areas and when occlusive dressings are used.[Ref]

References

1. "Product Information. Cortisporin Topical (hydrocortisone/neomycin/polymyxin B topical)." Monarch Pharmaceuticals Inc, Bristol, TN.

2. "Product Information. Cortisporin (bacitracin/HC/neomycin/polymyxin B topical)." Monarch Pharmaceuticals Inc, Bristol, TN.

Not all side effects for bacitracin / hydrocortisone / neomycin / polymyxin b topical may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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