Skip to Content

Azithromycin ophthalmic Side Effects

For the Consumer

Applies to azithromycin ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by azithromycin ophthalmic. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking azithromycin ophthalmic:

Less common:
  • Burning, redness, stinging, or other eye irritation
Rare
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • blurred vision
  • cough
  • decreased vision
  • discharge from the eye
  • fever
  • headache
  • hives or welts
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • pain or tenderness around the eyes and cheekbones
  • painful irritation of the clear front part of the eye
  • shortness of breath or troubled breathing
  • skin rash
  • stuffy or runny nose
  • swelling of the face
  • swelling or puffiness of the eyes
  • tightness of the chest or wheezing

Minor Side Effects

Some of the side effects that can occur with azithromycin ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Rare
  • Change in taste
  • dry eyes
  • loss of taste

For Healthcare Professionals

Applies to azithromycin ophthalmic: ophthalmic solution

Ocular

Very common (10% or more): Ocular discomfort (pruritus, burning, stinging) upon instillation
Common (1% to 10%): Eye irritation, blurred vision, sticky eye sensation, foreign body sensation upon instillation
Uncommon (0.1% to 1%): Conjunctival hyperemia, lacrimation increased upon instillation, erythema of the eyelid
Frequency not reported: Ocular reactions (burning, irritation upon instillation, contact dermatitis, corneal erosion, dry eye, eye pain, itching, ocular discharge, punctate keratitis, reduced visual acuity)
Postmarketing reports: Conjunctivitis, allergic conjunctivitis, keratitis, eyelid eczema, eyelid edema, eye allergy[Ref]

Hypersensitivity

Uncommon (0.1% to 1%): Hypersensitivity[Ref]

Dermatologic

Frequency not reported: Hives/urticaria, rash, facial swelling, periocular swelling
Postmarketing reports: Angioedema[Ref]

Nervous system

Frequency not reported: Dysgeusia[Ref]

Respiratory

Frequency not reported: Nasal congestion, sinusitis[Ref]

References

1. "Product Information. AzaSite (azithromycin ophthalmic)." Inspire Pharmaceuticals Inc, Durham, NC.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Not all side effects for azithromycin ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Hide