Arimidex Side Effects
Generic name: anastrozole
Note: This document contains side effect information about anastrozole. Some dosage forms listed on this page may not apply to the brand name Arimidex.
Applies to anastrozole: oral tablet.
Serious side effects of Arimidex
Along with its needed effects, anastrozole (the active ingredient contained in Arimidex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking anastrozole:
- Blurred vision
- bone pain
- chest pain or discomfort
- pounding in the ears
- slow or fast heartbeat
- swelling of the feet or lower legs
- Arm, back, or jaw pain
- chest tightness or heaviness
- cough producing mucus
- difficult or painful urination
- difficulty breathing
- dizziness, severe
- headache, continuing
- increased blood pressure
- lower back or side pain
- pain, tenderness, bluish color, or swelling of the foot or leg
- sore throat
- unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
- vaginal bleeding (unexpected and heavy)
Incidence not known
- Blistering, peeling, or loosening of the skin
- dark urine
- difficulty swallowing
- dry mouth
- general tiredness and weakness
- hives or welts, itching, skin rash
- incoherent speech
- increased urination
- joint or muscle pain
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
- light-colored stools
- loss of appetite
- metallic taste
- muscle weakness
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red skin lesions, often with a purple center
- red, irritated eyes
- sores, ulcers, or white spots in the mouth or on the lips
- stomach pain
- upper right abdominal pain
- weight loss
- yellow eyes and skin
Other side effects of Arimidex
Some side effects of anastrozole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Back pain
- body aches or pain
- decrease in height
- feeling of warmth
- flushing or redness of the skin, especially on the face and neck
- increased appetite
- lack or loss of strength
- mood or mental changes
- pain in the back, ribs, arms, or legs
- pain, general
- pelvic pain
- runny nose
- stomach discomfort or upset
- tender, swollen glands in the neck
- trouble in swallowing
- voice changes
- breast pain
- dryness of the vagina
- general feeling of discomfort or illness
- joint stiffness
- loss of hair
- numbness or tingling of the hands or feet
- trouble sleeping
- weight gain
Incidence not known
- Difficulty in moving
- muscle cramps or stiffness
- swollen joints
For Healthcare Professionals
Applies to anastrozole: compounding powder, oral tablet.
Very common (10% or more): Arthritis/arthralgia/arthrosis/joint disorder/joint pain/joint stiffness (36%), back pain (12%), bone pain (12%), osteoporosis (11%), fracture (10%)
Common (1% to 10%): Myalgia, anorexia
Uncommon (0.1% to 1%): Trigger finger[Ref]
Very common (10% or more): Nausea (20%), vomiting (11%)
Very common (10% or more): Fatigue/asthenia (19%), pain (17%), accidental injury (10%), lymphedema (10%), peripheral edema (10%)
Very common (10% or more): Headache (18%), depression (13%), insomnia (10%)
Common (1% to 10%): Dizziness, anxiety, paresthesia, hypertonia, cerebrovascular event (cerebrovascular accident, cerebral ischemia, cerebral infarct), somnolence, confusion, nervousness, carpal tunnel syndrome, sensory disturbances (e.g., taste loss and taste perversion)[Ref]
Very common (10% or more): Rash (11%)
Common (1% to 10%): Increased gamma GT, increased SGOT, increased SGPT, increased alkaline phosphatase
Uncommon (0.1% to 1%): Hepatobiliary events (e.g., increased bilirubin), hepatitis
Rare (less than 0.1%): Changes in liver function (liver inflammation, liver pain, liver swelling)[Ref]
Common (1% to 10%): Weight gain, hypercholesterolemia, weight loss, anorexia
Common (1% to 10%): Allergic reactions
Uncommon (0.1% to 1%): Urticaria
Rare (less than 0.1%): Anaphylaxis, anaphylactoid reaction
Common (1% to 10%): Cataracts[Ref]
Common (1% to 10%): Neoplasm, tumor flare
Frequently asked questions
- How do I take Arimidex on a cycle and how much?
- What happens when you stop taking Arimidex?
- Does anastrozole cause weight gain?
- How soon do the side effects of Arimidex start?
- Does anastrozole cause hair loss?
- How long do side effects last after stopping Arimidex?
- What does anastrozole do to your body?
- How much does Arimidex increase survival?
- How do I take anastrozole on a cycle and how much?
- What is Veridex used for?
More about Arimidex (anastrozole)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (74)
- Drug images
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: aromatase inhibitors
- En español
Related treatment guides
1. "Product Information. Arimidex (anastrozole)." Astra-Zeneca Pharmaceuticals (2001):
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
3. Cerner Multum, Inc. "Australian Product Information." O 0
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.