Amobarbital Side Effects
Medically reviewed by Drugs.com. Last updated on Jul 2, 2022.
For the Consumer
Applies to amobarbital: injection solution reconstituted
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of depression, thoughts of suicide, nervousness, emotional ups and downs, thinking that is not normal, anxiety, or lack of interest in life.
- Trouble breathing, slow breathing, or shallow breathing.
- Very bad irritation where the shot was given.
- This drug may cause tissue damage if the drug leaks from the vein. Tell your nurse if you have any redness, burning, pain, swelling, blisters, skin sores, or leaking of fluid where the drug is going into your body.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling sleepy.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to amobarbital: compounding powder, injectable powder for injection
The most commonly reported side effect was somnolence.[Ref]
Common (1% to 10%): Somnolence
Frequency not reported: Apnea, hypoventilation, postoperative atelectasis[Ref]
Frequency not reported: Exfoliative dermatitis, skin rashes[Ref]
Frequency not reported: Liver damage[Ref]
Frequency not reported: Megaloblastic anemia[Ref]
Frequency not reported: Injection site reactions[Ref]
Frequency not reported: Fever[Ref]
More about amobarbital
Related treatment guides
1. "Product Information. Amytal Sodium (amobarbital)." Lilly, Eli and Company (2001):
2. "Product Information. Amytal Sodium (amobarbital)." Marathon Pharmaceuticals (2010):
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.