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AK-Tob Side Effects

Generic Name: tobramycin ophthalmic

Note: This page contains information about the side effects of tobramycin ophthalmic. Some of the dosage forms included on this document may not apply to the brand name AK-Tob.

For the Consumer

Applies to tobramycin ophthalmic: ophthalmic ointment, ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by tobramycin ophthalmic (the active ingredient contained in AK-Tob). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking tobramycin ophthalmic:

Less common:
  • Itching, redness, swelling, or other sign of eye or eyelid irritation not present before use of this medicine
Symptoms of overdose:
  • Increased watering of the eyes
  • itching, redness, or swelling of the eyes or eyelids
  • painful irritation of the clear front part of the eye

Minor Side Effects

Some of the side effects that can occur with tobramycin ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Less common:
  • Burning or stinging of the eyes

Eye ointments usually cause your vision to blur for a few minutes after application.

For Healthcare Professionals

Applies to tobramycin ophthalmic: ophthalmic ointment, ophthalmic solution


Ocular side effects of tobramycin ophthalmic (the active ingredient contained in AK-Tob) include eyelid itching and swelling. Conjunctival erythema has also been reported.[Ref]


A case of allergic conjunctivitis and blepharitis associated with tobramycin ophthalmic (the active ingredient contained in AK-Tob) ointment has been reported. Hypersensitivity was confirmed by patch testing.[Ref]

Tobramycin ophthalmic has been associated with hypersensitivity reactions.[Ref]


1. "Product Information. Tobrex (tobramycin ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.

2. Caraffini S, Assalve D, Stingeni L, Lisi P "Allergic contact conjunctivitis and blepharitis from tobramycin." Contact Dermatitis 32 (1995): 186-7

Not all side effects for AK-Tob may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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