Aminoglycosides
What are Aminoglycosides?
Aminoglycosides are a class of antibiotics used mainly in the treatment of aerobic gram-negative bacilli infections, although they are also effective against other bacteria including Staphylococci and Mycobacterium tuberculosis. They are often used in combination with other antibiotics.
Aminoglycosides are thought to work by inhibiting protein synthesis inside bacteria. Kill rates of bacteria are increased when higher concentrations of aminoglycosides are present; however, the margin between a safe and a toxic dose is narrow and monitoring is often needed, although once daily dosing increases the safety window. Impairment of kidney function and hearing loss are the most common side effects of aminoglycosides. Aminoglycosides tend to be used when other less toxic antibiotics are contraindicated or ineffective.
Aminoglycosides are not well absorbed when given by mouth, so need to be given by injection by healthcare personnel.
List of Aminoglycosides
Drug Name | Avg. Rating | Reviews |
---|---|---|
paromomycin systemic (Pro) |
7 reviews | |
amikacin systemic (Pro) |
5 reviews | |
gentamicin systemic (Pro) Brand name: Garamycin |
3 reviews | |
streptomycin systemic (Pro) |
1 review | |
neomycin systemic (Pro) |
1 review | |
amikacin liposome systemic Brand name: Arikayce |
1 review | |
tobramycin systemic (Pro) Brand names: Tobi, Bethkis, TOBI Podhaler, Kitabis Pak | No reviews | |
plazomicin systemic (Pro) Brand name: Zemdri | No reviews | |
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). |
See also
Medical conditions treated or associated with aminoglycosides:
- Amebiasis
- Bacteremia
- Bacterial Endocarditis Prevention
- Bacterial Infection
- Beef Tapeworm Infection
- Bone infection
- Bowel Preparation
- Brucellosis
- Burns, External
- Cryptosporidiosis
- Cystic Fibrosis
- Diarrhea
- Dientamoeba fragilis
- Dog Tapeworm Infection
- Dwarf Tapeworm Infection
- Endocarditis
- Endometritis
- Febrile Neutropenia
- Fish Tapeworm Infection
- Giardiasis
- Hepatic Coma
- Hepatic Encephalopathy
- Intraabdominal Infection
- Joint Infection
- Kidney Infections
- Meningitis
- Mycobacterium avium-intracellulare, Treatment
- Nosocomial Pneumonia
- Pelvic Inflammatory Disease
- Peritonitis
- Plague
- Pneumonia
- Pork Tapeworm Infection
- Rabbit Fever
- Sepsis
- Shunt Infection
- Skin or Soft Tissue Infection
- Surgical Prophylaxis
- Tuberculosis, Active
- Urinary Tract Infection
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.