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Abbokinase Side Effects

Generic name: urokinase

Medically reviewed by Drugs.com. Last updated on Sep 2, 2023.

Note: This document provides detailed information about Abbokinase Side Effects associated with urokinase. Some dosage forms listed on this page may not apply specifically to the brand name Abbokinase.

Applies to urokinase: intravenous powder for injection.

Important warnings This medicine can cause some serious health issues

If possible before you receive urokinase, tell your doctor if you have a brain tumor or aneurysm, hemophilia or other bleeding disorder, high blood pressure, or if you have recently had a stroke, brain or spinal surgery, or medical emergency requiring CPR (cardiopulmonary resuscitation).

In an emergency situation it may not be possible to tell your caregivers about your health conditions. Make sure any doctor caring for you afterward knows you have received this medicine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Urokinase (the active ingredient contained in Abbokinase) increases your risk of bleeding, which can be severe or life-threatening. Call your doctor or seek emergency medical attention if you have bleeding that will not stop. Bleeding may occur from a surgical incision, or from the skin where a needle was inserted during a blood test or while receiving injectable medication. You may also have bleeding on the inside of your body, such as in your stomach or intestines, kidneys or bladder, brain, or within the muscles.

Call your doctor at once if you have signs of bleeding inside your body, such as:

Some side effects may occur during or within 1 hour after the injection. Tell your caregiver right away if you feel chilled or feverish, nauseated, light-headed, or have chest tightness, back pain, trouble breathing, or fast heartbeats.

Also call your doctor at once if you have:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to urokinase: intravenous powder for injection.

General

The most common and severe adverse reaction was hemorrhage, with puncture site being the most frequent location.[Ref]

Hematologic

Cardiovascular

Gastrointestinal

Nervous system

Other

Genitourinary

Musculoskeletal

Immunologic

Hepatic

Renal

Respiratory

Dermatologic

Local

Metabolic

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. (2016) "Product Information. Kinlytic (urokinase)." ImaRx Therapeutics, Inc

Further information

Abbokinase side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.