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Urokinase Dosage

Medically reviewed by Last updated on Feb 22, 2024.

Applies to the following strengths: 250000 intl units; 5000 intl units; 9000 intl units

Usual Adult Dose for Pulmonary Embolism

Initial dose: 4400 international units/kg IV at a rate of 90 mL/hr over 10 minutes

Maintenance dose: 4400 international units/kg/hr IV at a rate of 15 mL for 12 hours



Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available



Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Storage requirements: Refrigerate powder at 2 to 8C (36 to 46F).

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

IV compatibility: This drug should not be mixed with other medicinal products.


Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.