Safinamide is monoamine oxidase inhibitor type B (MAO-B). safinamide works by allowing a chemical called dopamine (DOE pa meen) to work for longer periods of time in the brain. Low levels of dopamine in the brain are associated with Parkinson's disease. Safinamide is given with levodopa and carbidopa...
Selective reversible MAO-B inhibitor. Used as an adjunct to levodopa-carbidopa for the symptomatic treatment of parkinsonian syndrome (e.g., parkinsonism, Parkinson disease [paralysis agitans]) in patients who experience “off” episodes (i.e., time when drug effect wears off and parkinsonian...
Safinamide Dosage Applies to the following strengths: 50 mg; 100 mg Usual Adult Dose for: Parkinson's Disease Additional dosage information: Renal Dose Adjustments Liver Dose Adjustments Dose Adjustments Precautions Dialysis Other Comments Usual Adult Dose for Parkinson's Disease Initial dose: 50...
Safinamide Interactions There are 488 drugs known to interact with safinamide , along with 4 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 72 are major, 414 are moderate, and 2 are minor. Does safinamide interact with my other drugs? Enter medications to...
Safinamide Side Effects Medically reviewed by Philip Thornton, DipPharm . Last updated on Feb 11, 2025. Serious side effects Other side effects Professional info Applies to safinamide: oral tablet . Precautions It is very important that your doctor check your progress at regular visits to allow for...
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Safinamide Disease Interactions There are 4 disease interactions with safinamide. Major Safinamide (applies to safinamide) hepatic impairment Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease Safinamide is contraindicated in patients with severe hepatic dysfunction...
Safinamide (Ingredient) The information below refers to products available in the United States that contain safinamide . Products containing safinamide safinamide systemic Brand name: Xadago Drug class: dopaminergic antiparkinsonism agents Safinamide systemic is used in the treatment of...
Safinamide Alternatives Compared View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Safinamide Carbidopa / levodopa Sinemet (carbidopa / levodopa) Enter another drug to compare View side-by-side comparisons of medication uses, ratings, cost, side effects...
Safinamide (Oral) Uses Before taking Dosage Warnings Side effects Brand names Uses for safinamide Safinamide is used in combination with levodopa and carbidopa to treat adults with Parkinson's disease who are having "off" episodes. This medicine is a MAO-B inhibitor that works to increase and...
Safinamide use while Breastfeeding Drugs containing Safinamide: Xadago Summary Drug levels Infants Lactation / breastmilk Alternate drugs Safinamide Levels and Effects while Breastfeeding Summary of Use during Lactation No information is available on the use of safinamide during breastfeeding...
