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Generic Name: oxymetazoline topical (OX ee me TAZ o leen TOP i kal)
Brand Names: Rhofade

What is Rhofade?

Rhofade (oxymetazoline) is a decongestant that shrinks blood vessels. Dilated blood vessels under the skin can cause redness.

Rhofade is used to treat facial redness caused by rosacea.

Rhofade may also be used for purposes not listed in this medication guide.

Important information

Do not take Rhofade by mouth. Topical medicine is for use only on the skin.

Rinse with water if this medicine gets in your eyes.

Before taking this medicine

You should not use Rhofade if you are allergic to oxymetazoline.

To make sure Rhofade is safe for you, tell your doctor if you have:

  • heart disease, high blood pressure;

  • blood circulation problems;

  • glaucoma; or

  • peripheral vascular disease such as Raynaud's syndrome, Buerger's disease, scleroderma, or Sj√∂gren's syndrome.

It is not known whether Rhofade will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether oxymetazoline topical passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Rhofade is not approved for use by anyone younger than 18 years old.

How should I use Rhofade?

Use Rhofade exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Topical medicine is for use only on the skin. Do not use this medicine on open wounds or irritated skin. If this medicine gets in your eyes, nose, mouth, or vagina, rinse with water.

Apply a thin layer of Rhofade to cover the entire face. Do not apply near your eyes or mouth.

Wash your hands after applying this medicine.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Call your doctor if your symptoms do not improve, or if they get worse.

Store at room temperature away from moisture and heat.

Rhofade dosing information

Usual Adult Dose for Acne Rosacea:

Apply a thin layer to cover the entire face (e.g., forehead, nose, cheeks, chin) once a day

-The eyes and lips should be avoided during application.
-Patients should wash their hands immediately after application.

Use: Topical treatment of persistent facial erythema associated with rosacea

Dosage Information (comprehensive)

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

An overdose of oxymetazoline is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

What should I avoid while using Rhofade?

Avoid getting this medicine in your eyes or mouth.

Rhofade side effects

Get emergency medical help if you have signs of an allergic reactionto Rhofade: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • worsening of your rosacea symptoms;

  • numbness, tingling, cold feeling in your hands or feet;

  • pale or purple appearance in your fingers or toes; or

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights.

Common Rhofade side effects may include:

  • skin redness or itching;

  • pain; or

  • other skin reactions.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Side Effects (complete list)

What other drugs will affect Rhofade?

Other drugs may interact with oxymetazoline topical, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Rhofade.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Rhofade only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2018 Cerner Multum, Inc. Version: 1.01.

Date modified: June 01, 2017
Last reviewed: May 05, 2017