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Rhofade (oxymetazoline topical) Drug Interactions

A total of 74 drugs are known to interact with Rhofade (oxymetazoline topical).

  • 8 major drug interactions
  • 66 moderate drug interactions

Show all medications in the database that may interact with Rhofade (oxymetazoline topical).

Check for interactions with Rhofade (oxymetazoline topical)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Rhofade (oxymetazoline topical)

  • albuterol (ProAir HFA, Ventolin, Ventolin HFA, Proventil, Proventil HFA, Respirol, ProAir RespiClick, AccuNeb, Airet, Volmax, Vospire ER)
  • Aleve (naproxen)
  • Benadryl (diphenhydramine)
  • biotin (Hair, Skin & Nails, Appearex)
  • famotidine (Pepcid, Pepcid AC, Heartburn Relief, Acid Reducer-Famotidine, Pepcid AC Maximum Strength, Pepcid Oral Suspension, Acid Control, Acid Reducer Original Strength, Acid Reducer Maximum Strength, Heartburn Relief Maximum Strength, Acid Controller Original Strength, Fluxid, Pepcid RPD, Mylanta AR, Pepcid AC Chewable Tablets, Pepcid AC Maximum Strength Tablets, Acid Controller Maximum Strength)
  • magnesium oxide (Mag-Ox, Mag-Oxide, Uro-Mag, Mag-200, Mag-Ox 400, MagGel, Phillips' Cramp-free, Mag-Caps)
  • metronidazole topical (MetroGel, MetroGel-Vaginal, MetroCream, Noritate, Rosadan, MetroLotion, Vandazole, Nuvessa, Rozex, Vitazol, Rosaclear)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pantoprazole (Protonix, Protonix IV)
  • prednisone (Deltasone, Rayos, Sterapred DS, Sterapred, Prednicot, Meticorten, Liquid Pred, Orasone, Prednicen-M)
  • ProAir HFA (albuterol)
  • pseudoephedrine (Sudafed Congestion, SudoGest, Sudafed 12-Hour, Entex, Efidac, Silfedrine, Suphedrine, Chlor-Trimeton Nasal Decongestant, Nexafed Nasal Decongestant, nasofed, Suphedrin, ElixSure Congestion, Children's Dimetapp Decongestant Infant, Allermed, Novafed, Cenafed, Genaphed, Ridafed, Seudotabs, Sudrine, Superfed, Afrinol, Zephrex-D, Sudafed Children's Nasal Decongestant, Decofed Liquid, Decofed, Kid Kare Drops, Myfedrine, Sudodrin, Elixsure Decongestant, Unifed, Sudafed 24-Hour, Contac Cold, Drixoral Decongestant Non-Drowsy, SudoGest 12 Hour, 12 Hour Decongestant, 12 Hour Nasal Decongestant)
  • Soolantra (ivermectin topical)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Tramedo, GenRx Tramadol, ConZip, Zydol, Ryzolt, Larapam SR, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Rybix, Ultram ODT)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin B6 (pyridoxine)
  • Vitamin C (ascorbic acid)
  • Vitamin D3 (cholecalciferol)
  • Voltaren Gel (diclofenac topical)
  • Zyrtec (cetirizine)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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