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Rayaldee

Generic Name: calcifediol (KAL sif e DYE ol)
Brand Name: Rayaldee

Medically reviewed by Drugs.com on May 26, 2017 – Written by Cerner Multum

What is Rayaldee?

Rayaldee is a vitamin D3. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Rayaldee is used to treat hyperparathyroidism (overactive parathyroid glands) in people who have stage 3 or 4 chronic kidney failure and low vitamin D levels. This medicine is not for people who are receiving dialysis.

Rayaldee may also be used for purposes not listed in this medication guide.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Rayaldee if you have ever had an allergic reaction to vitamin D.

To make sure Rayaldee is safe for you, tell your doctor if you have:

  • heart problems; or

  • high levels of calcium in your blood (hypercalcemia).

It is not known whether Rayaldee will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether calcifediol passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

How should I take Rayaldee?

Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine at bedtime each day.

Do not crush, chew, break, or open an extended-release capsule. Swallow it whole.

While using Rayaldee, you may need frequent blood tests.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include vomiting, constipation, loss of appetite, feeling tired or irritable, muscle weakness, feeling very thirsty or hot, or urinating less than usual.

What should I avoid while taking Rayaldee?

Ask a doctor or pharmacist before using any vitamins or mineral supplements. Many non-prescription dietary supplements contain calcium or vitamin D. Taking certain products together can cause you to get too much of these ingredients.

Rayaldee side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • shortness of breath (even with mild exertion), swelling, rapid weight gain;

  • high levels of calcium in your blood--nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, confusion, lack of energy, or tired feeling; or

  • low red blood cells (anemia)--pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating.

Common side effects may include:

  • constipation; or

  • runny or stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Rayaldee?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Tell your doctor about all your current medicines and any you start or stop using, especially:

This list is not complete and many other drugs can interact with Rayaldee. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Give a list of all your medicines to any healthcare provider who treats you.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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