Medically reviewed on January 5, 2018
What is Pro-Chlo?
Chlophedianol is a cough suppressant. It affects the signals in the brain that trigger cough reflex.
Pro-Chlo may also be used for purposes not listed in this medication guide.
Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Before taking this medicine
Do not use Pro-Chlo if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
You should not use this medicine if you are allergic to chlophedianol, phenylephrine, or pyrilamine.
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:
any type of breathing disorder;
blockage in your intestines;
bladder obstruction or other urination problems;
cough with mucus;
liver or kidney disease;
heart disease, high blood pressure;
a thyroid disorder; or
FDA pregnancy category C. It is not known whether Pro-Chlo will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.
Chlophedianol, phenylephrine, and pyrilamine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.
How should I take Pro-Chlo?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.
Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken a cough or cold medicine within the past few days.
Store at room temperature away from moisture and heat. Do not freeze.
What happens if I miss a dose?
Since cough or cold medicine is taken when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Pro-Chlo?
Pro-Chlo may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.
Ask a doctor or pharmacist before using any other cold, allergy, cough, or sleep medicine. Antihistamines, antitussives, and decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine, antitussive, or decongestant.
Drinking alcohol can increase certain side effects of chlophedianol, phenylephrine, and pyrilamine.
Pro-Chlo side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
chests tightness, wheezing, shortness of breath;
a light-headed feeling, like you might pass out;
little or no urinating;
severe restless feeling or being unable to sleep.
Common side effects may include:
mild dizziness or drowsiness;
dry mouth, nose, or throat;
feeling restless or excited (especially in children);
blurred vision; or
sleep problems (insomnia).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Pro-Chlo?
Ask a doctor or pharmacist before using Pro-Chlo if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.
Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking Pro-Chlo with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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