Generic name: guaifenesin and phenylephrine [ gwye-FEN-e-sin-and-FEN-il-EFF-rin ]
Brand names: Aldex G, Deconex IR, Gilphex TR, Giltuss Sinus and Congestion, Maxi-Tuss PE Jr, ... show all 25 brands Mucus Relief Sinus, Supress-PE, Aldex G, Aquatab D, D-Phen 1000, Deconex, Deconex IR, Donatussin Drops, Duravent PE, Gilphex TR, Giltuss Sinus and Congestion, Liquibid-PD, Maxi-Tuss PE Jr, MucaphEd, Mucus Relief Sinus, Nariz, Prolex D, Sudafed PE Non-Drying Sinus, Supress-PE, Xpect-PE
Drug class: Upper respiratory combinations
What is MucaphEd?
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.
Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).
MucaphEd may also be used for purposes not listed in this medication guide.
MucaphEd side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
MucaphEd may cause serious side effects. Stop using MucaphEd and call your doctor at once if you have:
fast, pounding, or uneven heartbeat; or
severe anxiety or nervousness.
Common side effects of MucaphEd may include:
dry mouth, nose, or throat;
feeling excited or restless (especially in children);
sleep problems (insomnia); or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
Before taking this medicine
You should not use MucaphEd if you are allergic to it.
Do not use MucaphEd if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Ask a doctor or pharmacist if it is safe for you to take this medication if you have:
overactive thyroid; or
enlarged prostate or problems with urination.
It is not known if this medication may be harmful to an unborn baby. Do not use MucaphEd without medical advice if you are pregnant.
Guaifenesin and phenylephrine may pass into breast milk and may harm a nursing baby. Decongestants may also slow breast milk production. Do not use this medicine without medical advice if you are breast-feeding a baby.
How should I take MucaphEd?
Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.
Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole.
Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Since MucaphEd is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking MucaphEd?
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of guaifenesin and phenylephrine.
Ask a doctor or pharmacist before using any other cough, cold, or allergy medicine. MucaphEd are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug.
What other drugs will affect MucaphEd?
Ask a doctor or pharmacist before using MucaphEd if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.
Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking MucaphEd with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
More about MucaphEd (guaifenesin / phenylephrine)
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- During pregnancy
- Drug class: upper respiratory combinations
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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