Dextromethorphan, guaifenesin, and phenylephrine
Generic name: dextromethorphan, guaifenesin, and phenylephrine [ dex-troe-meth-OR-fan, gwye-FEN-e-sin, fen-il-EFF-rin ]
Brand names: Broncotron-D, Duravent DM, Giltuss, Mucinex Fast-Max Severe Congestion and Cough, Phlemex Forte, ... show all 89 brands Robitussin Children's Cough and Cold CF, Tusicof, Tussin CF, Vanacof DM, Z-tuss DM, Tussex, Tussafed-EX, Sinutuss DM, GDP-EX, Duraphen DM, TriTuss, TriTuss-ER, Tussafed-EX Drops, Certuss-D, Dacex-PE, Anextuss, Dexcon-PE, Zotex LAX, Dacex-DM, Dexcon-DM, Duraphen II DM, Duraphen Forte, Maxiphen DM, G-Phen DM, Despec DM Syrup, Phlemex-PE, Guaphen Forte, Guaphen II DM, Z-Dex, Robafen CF, DuraMAX, Tusso-XR, Tusso-DM, Robitussin Cough and Cold CF, Ambi 40/1000/60, Maxiphen-G DM, Robitussin Pediatric Cough and Cold CF, Deconex DM, PDM GG, ExeTuss-DM, Endacon DM, Giltuss TR, Q-Tussin CF, Tusso-DMR, Deconex DMX, Execof ER, Dynatuss EX, Zotex, Robitussin Cough and Cold CF To Go, Zotex-EX, Endacon, Robitussin Cough and Cold CF Max, Mucinex Children's Multi-Symptom Cold, Supress-DX, Tussi-Pres, Tussi-Pres Pediatric, Pres Gen Pediatric, Pres Gen, Robitussin Multi-Symptom Cold, Robitussin Peak Cold Max Strenth Multi-S, G-Tusicof, Adult Severe Congestion and Cough, Giltuss Pediatrics, Desgen DM (Phenylephrine), G-Supress DX, Tusslin, Desgen Pediatric, G-Tron Ped, Broncotron Ped, Tusslin Pediatric, Nivanex DMX, Relhist DMX, Giltuss Cough and Cold, Children Giltuss Cough and Cold, VanaTab DM, Tukol Cough and Cold, Robitussin Peak Cold Multi-Symptom Cold, Deconex DMX Poly, Mucinex Fast-Max Severe Congestion and Cough Clear and Cool, Mucinex FreeFrom Severe Congestion and Cough, Mucinex Children's Congestion and Cough Very Berry, Mucinex Children's FreeFrom Multi-Symptom Cold Stuffy Nose, VanaCof DMX, Mucinex Junior Cough and Cold
Dosage forms: oral liquid (10 mg-200 mg-5 mg/30 mL; 10 mg-200 mg-5 mg/5 mL; 15 mg-350 mg-10 mg/5 mL; 18 mg-200 mg-10 mg/15 mL; 20 mg-200 mg-10 mg/10 mL; 20 mg-400 mg-10 mg/20 mL; 20 mg-400 mg-10 mg/5 mL; 28 mg-388 mg-10 mg/5 mL; 29 mg-390 mg-10 mg/5 mL; 5 mg-100 mg-2.5 mg; 5 mg-100 mg-2.5 mg/5 mL; 5 mg-100 mg-2.5 mg/mL; 5 mg-50 mg-2.5 mg/5 mL; 5 mg-50 mg-2.5 mg/mL; 5 mg-75 mg-2.5 mg/5 mL), ... show all 5 dosage forms oral suspension (20 mg-200 mg-5 mg/5 mL), oral syrup (10 mg-100 mg-5 mg/5 mL; 15 mg-100 mg-5 mg/5 mL; 15 mg-300 mg-10 mg/5 mL; 25 mg-175 mg-12.5 mg/5 mL; 30 mg-200 mg-10 mg/5 mL), oral tablet (10 mg-200 mg-5 mg; 15 mg-350 mg-12 mg; 15 mg-380 mg-10 mg; 15 mg-395 mg-10 mg; 17.5 mg-385 mg-10 mg; 17.5 mg-400 mg-10 mg; 20 mg-400 mg-10 mg; 28 mg-388 mg-10 mg; 5 mg-100 mg-2.5 mg; 9 mg-198 mg-5 mg), oral tablet, extended release (30 mg-1000 mg-20 mg; 30 mg-1200 mg-30 mg)
Drug class: Upper respiratory combinations
What is dextromethorphan, guaifenesin, and phenylephrine?
Dextromethorphan is a cough suppressant that affects signals in the brain that trigger cough reflex. Guaifenesin is an expectorant that loosens congestion in your chest and throat. Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages.
Dextromethorphan, guaifenesin, and phenylephrine is a combination medicine used to treat cough, stuffy nose, and chest congestion caused by allergies, the common cold, or the flu.
dextromethorphan, guaifenesin, and phenylephrine will not treat a cough that is caused by smoking, asthma, or emphysema.
There are many brands and forms of this medicine available. Not all brands are listed on this leaflet.
Dextromethorphan, guaifenesin, and phenylephrine may also be used for purposes not listed in this medication guide.
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Before taking this medicine
You should not use this medicine if you are allergic to dextromethorphan, guaifenesin, or phenylephrine.
Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
Ask a doctor or pharmacist if this medicine is safe to use if you have:
a thyroid disorder;
epilepsy or other seizure disorder;
pheochromocytoma (an adrenal gland tumor); or
cough with mucus, or cough caused by emphysema or chronic bronchitis.
This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).
Ask a doctor before using this medicine if you are pregnant or breast-feeding.
How should I take dextromethorphan, guaifenesin, and phenylephrine?
Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.
Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.
Do not crush, chew, or break an extended-release tablet. Swallow it whole.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.
If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.
Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.
What happens if I miss a dose?
Since cough or cold medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking dextromethorphan, guaifenesin, and phenylephrine?
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Drinking alcohol can increase certain side effects of this medicine.
Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.
dextromethorphan, guaifenesin, and phenylephrine side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:
little or no urination;
fast or slow heartbeats;
confusion, dizziness, feeling unsteady;
nervousness, sleep problems (insomnia);
severe headache, blurred vision, pounding in your neck or ears;
slow breathing; or
unusual changes in mood or behavior.
Common side effects of dextromethorphan, guaifenesin, and phenylephrine may include:
sleep problems (insomnia); or
feeling nervous, restless, or irritable.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect dextromethorphan, guaifenesin, and phenylephrine?
Avoid using dextromethorphan, guaifenesin, and phenylephrine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures). Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed in this medication guide.
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- Drug class: upper respiratory combinations
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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