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Dextromethorphan / Guaifenesin / Phenylephrine Dosage

Medically reviewed by Drugs.com. Last updated on June 28, 2019.

Applies to the following strengths: 5 mg-50 mg-2.5 mg/5 mL; 10 mg-200 mg-5 mg/5 mL; 10 mg-100 mg-5 mg/5 mL; 5 mg-100 mg-2.5 mg/2.5 mL; 20 mg-200 mg-10 mg/10 mL; 40 mg-200 mg-20 mg/10 mL; 23 mg-600 mg-9 mg; 14 mg-288 mg-7 mg; 30 mg-600 mg-10 mg; 25 mg-175 mg-12.5 mg/5 mL; 30 mg-200 mg-10 mg/5 mL; 5 mg-50 mg-2.5 mg/mL; 30 mg-600 mg-15 mg; 20 mg-200 mg-5 mg/5 mL; 15 mg-350 mg-10 mg/5 mL; 5 mg-100 mg-2.5 mg/mL; 15 mg-100 mg-5 mg/5 mL; 20 mg-100 mg-10 mg/5 mL; 25 mg-600 mg-20 mg; 15 mg-395 mg-10 mg; 30 mg-600 mg-20 mg; 15 mg-380 mg-10 mg; 20 mg-400 mg-10 mg/20 mL; 5 mg-100 mg-2.5 mg/5 mL; 30 mg-900 mg-30 mg; 15 mg-390 mg-10 mg; 17.5 mg-385 mg-10 mg; 17.5 mg-400 mg-10 mg; 20 mg-1200 mg-40 mg; 5 mg-75 mg-2.5 mg/5 mL; 20 mg-400 mg-10 mg/5 mL; 20 mg-400 mg-10 mg; 28 mg-388 mg-10 mg/5 mL; 7.5 mg-88 mg-2.5 mg/mL; 15 mg-300 mg-10 mg/5 mL; 29 mg-390 mg-10 mg/5 mL; 28 mg-388 mg-10 mg; 9 mg-198 mg-5 mg; 18 mg-200 mg-10 mg/15 mL; 10 mg-200 mg-5 mg/30 mL; 60 mg-600 mg-40 mg; 25 mg-550 mg-20 mg; 20 mg-800 mg-20 mg; 30 mg-1200 mg-30 mg; 10 mg-200 mg-5 mg; 45 mg-1200 mg-25 mg; 60 mg-1000 mg-40 mg; 30 mg-1000 mg-20 mg; 15 mg-350 mg-12 mg

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough and Nasal Congestion

Dose referred to by strength of dextromethorphan/guaiFENesin/phenylephrine (in mg) per unit of measurement:

Oral liquids (liquid/drops/solution/syrup):
***LIQUID DOSE VOLUMES ARE HIGHLY VARIABLE (1 mL to 60 mL/dose). THE MANUFACTURER PRODUCT INFORMATION SHOULD BE CONSULTED***

5/50/2.5 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day

5/75/2.5 per 5 mL: 20 mL every 4 hours, maximum 6 doses per day

10/100/5 per 5 mL : 10 mL every 4 hours, maximum 6 doses per day

10/200/5 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day

15/100/5 per 5 mL: 10 mL every 4 hours, maximum 6 doses per day

15/350/10 per 5 mL: 5 mL every 4 hours, maximum 6 doses per day

15/350/10 per 5 mL: 5 mL every 4 hours, maximum 6 doses per day

20/400/10 per 5 mL: 5 mL every 4 hours, maximum 6 doses per day

28/388/10 per 5 mL: 5 mL every 6 hours, maximum 4 doses per day

30/200/10 per 5 mL: 5 mL every 6 hours, maximum 4 doses per day


18/200/10 per 15 mL: 15 mL every 4 hours, maximum 6 doses per day


20/400/10 per 20 mL: 20 mL every 4 hours, maximum 6 doses per day


10/200/5 per 30 mL: 60 mL every 4 hours, maximum 6 doses per day


Oral solids (tablets/caplets):

9/198/5 per tablet: 2 tablets every 4 hours, maximum 6 doses per day

10/200/5 per caplet: 2 caplets every 4 hours, maximum 6 doses per day

15/380/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day

15/395/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day

17.5/385/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day

20/400/10 per tablet: 1 tablet every 4 hours, maximum 6 doses per day

28/388/10 per tablet: 1 tablet every 4 to 8 hours, maximum 4 doses per day

Usual Pediatric Dose for Cough and Nasal Congestion

Dose referred to by strength of dextromethorphan/guaiFENesin/phenylephrine (in mg) per unit of measurement:

Oral liquids (liquid/drop/solution/syrup):
***LIQUID DOSE VOLUMES ARE HIGHLY VARIABLE (1 mL to 60 mL/dose). THE MANUFACTURER PRODUCT INFORMATION SHOULD BE CONSULTED. ***

5/50/2.5 per 1 mL
2 to under 6 years= 1 mL every 4 hours, maximum 6 doses per day

5/100/2.5 per 1 mL
6 to under 12 years= 2 mL every 4 hours, maximum 6 doses per day

7.5/88/2.5 per 1 mL
6 to under 12 years: 2 mL every 6 to 8 hours
2 to under 6 years: 1 mL every 6 to 8 hours


5/50/2.5 per 5 mL
6 to 12 years: 10 mL every 4 hours, maximum 6 doses per day
4 to under 6 years: 5 mL every 4 hours, maximum 6 doses per day

5/75/2.5 per 5 mL
12 years and older: 20 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 10 mL every 4 hours, maximum 6 doses per day
2 to under 6 years: 5 mL every 4 hours, maximum 6 doses per day

10/100/5 per 5 mL
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 5 mL every 4 hours, maximum 6 doses per day

10/200/5 per 5 mL
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 5 mL every 4 hours, maximum 6 doses per day
2 to under 6 years: 2.5 mL every 4 hours, maximum 6 doses per day

15/100/5 per 5 mL
12 years and older: 10 mL every 4 hours, maximum 6 doses per day
6 to 12 years: 5 mL every 4 hours, maximum 6 doses per day

15/350/10 per 5 mL
12 years and older: 5 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 2.5 mL every 4 hours, maximum 6 doses per day

15/350/10 per 5 mL
12 years and older: 5 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 2.5 mL every 4 hours, maximum 6 doses per day

20/400/10 per 5 mL
12 years and older: 5 mL every 4 hours, maximum 6 doses per day

28/388/10 per 5 mL
12 years and older: 5 mL every 6 hours, maximum 4 doses per day
6 to under 12 years: 2.5 mL every 6 hours, maximum 4 doses per day
2 to under 6 years: 1.25 mL every 6 hours, maximum 4 doses per day

30/200/10 per 5 mL
12 years and older: 5 mL every 6 hours, maximum 4 doses per day


18/200/10 per 15 mL
12 years and older: 15 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 7.5 mL every 4 hours, maximum 6 doses per day


20/400/10 per 20 mL
12 years and older: 20 mL every 4 hours, maximum 6 doses per day


10/200/5 per 30 mL
12 years and older: 60 mL every 4 hours, maximum 6 doses per day
6 to under 12 years: 30 mL every 4 hours, maximum 6 doses per day


Oral solids (tablets/caplets):

9/198/5 per tablet:
12 years and older: 2 tablets every 4 hours, maximum 6 doses per day
6 to under 12 years: 1 tablet every 4 hours, maximum 6 doses per day

10/200/5 per caplet:
12 years and older: 2 caplets every 4 hours, maximum 6 doses per day
6 to under 12 years: 1 caplet every 4 hours, maximum 6 doses per day


15/380/10 and 15/395/10 per tablet:
12 years and older: 1 tablet every 4 hours, maximum 6 doses per day
6 to under 12 years: 1/2 tablet every 4 hours, maximum 6 doses per day

17.5/385/10 per tablet:
12 years and older: 1 tablet every 4 hours, maximum 6 doses per day
6 to under 12 years: 1/2 tablet every 4 hours, maximum 3 doses per day

20/400/10 per tablet:
12 years and older: 1 tablet every 4 hours, maximum 6 doses per day
6 to under 12 years: 1/2 tablet every 4 hours, maximum 6 doses per day

28/388/10 per tablet:
12 years and older: 1 tablet every 4 to 8 hours, maximum 4 doses per day
6 to under 12 years: 1/2 tablet every 4 to 8 hours, maximum 4 doses per day

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
-Current use of a monoamine oxidase inhibitor (MAOI) or use within 14 days of stopping a MAOI.

Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.